ID A0A0L8HH33_OCTBM Unreviewed; 887 AA.
AC A0A0L8HH33;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=OCBIM_22015574mg {ECO:0000313|EMBL:KOF88080.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF88080.1};
RN [1] {ECO:0000313|EMBL:KOF88080.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF88080.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF88080.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR EMBL; KQ418267; KOF88080.1; -; Genomic_DNA.
DR RefSeq; XP_014772650.1; XM_014917164.1.
DR RefSeq; XP_014772651.1; XM_014917165.1.
DR AlphaFoldDB; A0A0L8HH33; -.
DR STRING; 37653.A0A0L8HH33; -.
DR EnsemblMetazoa; Ocbimv22015574m; Ocbimv22015574m.p; Ocbimv22015574m.g.
DR EnsemblMetazoa; XM_014917164.1; XP_014772650.1; LOC106870927.
DR EnsemblMetazoa; XM_014917165.1; XP_014772651.1; LOC106870927.
DR GeneID; 106870927; -.
DR KEGG; obi:106870927; -.
DR OMA; XYMLQRT; -.
DR OrthoDB; 276400at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 31..99
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 326..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 100555 MW; 09E63B6EE6ACF330 CRC64;
MAWSPEENGL RQILQLLKES QSPDTAAQRA VQQKLEELNT YPDFNNYLIF VLTKLKSEDD
PTRSLSGLIL KNNVRAHFEK FPSEVTNFIK SECLQSIGDS SPLIRATIGI LITTIVAKGE
LRNWPELLPS LCQCLDSEDY SVCEGAFGAM QKICEDSTEA LDSDLVNRPL NILIPKFLHF
FKHNSAKIRS HAIACVNQFI ISRTQALMMH IDSFIENLFY LASDEDTEVR KNVCRALVML
VEVRMDRLIP HINDIIGYMM LRTQDDDDAV SLEACEFWLS LAEQPICKDV LAPHIMRLVP
ILVKGMKYSE IDIILLKGDV EEDATVPDKE SDIKPRFHRS RTHSQKHQEG EEDGEYSDEG
FDDDDSLSDW NLRKCSAAAL DVLANVFRDE LLPILLPILK ETLFHEDWDI KESGILVLGA
IAEGCMTGMV PHLPELIPYL INCLADKKAL VRSITCWTLS RYAHWVVGQQ HELYLKPLMT
ELLKCVLDTN KRVQEAACSA FATLEEEACT ELVPYLGYIL ETLVFAFNKY QHKNLLILYD
AIGTLADSVG HHLNKPEYVN LLMPPLIQKW NVLKDEDKDL FPLLECLSSV ATALQSGFLP
YCEPVYKRCV SLVEQTLNQN FANLTHPEQY DPPDKDFMIV ALDLLSGLAE GLEHHIEGLV
ANSNILKLLF QCMQDPMPEV RQSSFALLGD LTKACFQHVK PCIGEFMPIL GANLNPEYIS
VCNNATWAIG EISIKMGHEI QPYINLVVTP LIEIINRPNT PKTLLENTAI TIGRLGLVCP
QEVAPMLQQF IRQWCTSLRN IRDNEEKDSA FRGVCNMINV NPAGVVQDFI FFCDAVASWV
HPKHDLKEMF YKILHGFKQQ VGDENWSKFS DQFPQPLRER LAVNYGV
//
