ID A0A0L8HP67_OCTBM Unreviewed; 368 AA.
AC A0A0L8HP67;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
DE Flags: Fragment;
GN ORFNames=OCBIM_22011046mg {ECO:0000313|EMBL:KOF90525.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF90525.1};
RN [1] {ECO:0000313|EMBL:KOF90525.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF90525.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF90525.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}. Mitochondrion intermembrane
CC space {ECO:0000256|ARBA:ARBA00004569}.
CC -!- SIMILARITY: Belongs to the MICU1 family. MICU1 subfamily.
CC {ECO:0000256|ARBA:ARBA00038333}.
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DR EMBL; KQ417740; KOF90525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8HP67; -.
DR EnsemblMetazoa; Ocbimv22011043m; Ocbimv22011043m.p; Ocbimv22011046m.g.
DR EnsemblMetazoa; XM_014915518.1; XP_014771004.1; LOC106869687.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006851; P:mitochondrial calcium ion transmembrane transport; IEA:InterPro.
DR CDD; cd15900; EFh_MICU; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039800; MICU1/2/3.
DR PANTHER; PTHR12294:SF1; CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12294; EF HAND DOMAIN FAMILY A1,A2-RELATED; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00022792};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022792};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 110..145
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 303..338
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF90525.1"
SQ SEQUENCE 368 AA; 42204 MW; 353569982151EA80 CRC64;
IVEYENRIRA YSTPDKIFRY FATLKVLNSE TSEYEICMTP ADFVRSITPG VKQPDGLGLD
QFRKFDPKKD SLHEDYPELE LGEHSIFYKL GQSGLISFSD YILLLTVLST PQRNFEIAFQ
MFDLNGDGNV DAEEFEKVQQ IVMNQTSMGM RHRDRSTTGN VNKGVSSALS TFFFGPDAKK
KLTVENFLDF QLQLQREILQ IEFERFVTEP GPNATIKEKE FGAILLAYAG LPDNKKVRML
KRVKKSYKDH SKGITLNEYI DFWKFLKSIN DVDTALSFYH LAGVSIDKET LKHVAKTVAN
VQLTDHLVDL VFTIFDENND GQLSNKEFVH VMKQRVMRGL EKPKDTGFVK LINAMIKCAI
YQTTSMFD
//
