ID A0A0L8HUE8_OCTBM Unreviewed; 387 AA.
AC A0A0L8HUE8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=OCBIM_22005859mg {ECO:0000313|EMBL:KOF92848.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF92848.1};
RN [1] {ECO:0000313|EMBL:KOF92848.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF92848.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF92848.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ417280; KOF92848.1; -; Genomic_DNA.
DR RefSeq; XP_014769317.1; XM_014913831.1.
DR AlphaFoldDB; A0A0L8HUE8; -.
DR STRING; 37653.A0A0L8HUE8; -.
DR EnsemblMetazoa; Ocbimv22005859m; Ocbimv22005859m.p; Ocbimv22005859m.g.
DR EnsemblMetazoa; XM_014913831.1; XP_014769317.1; LOC106868528.
DR GeneID; 106868528; -.
DR KEGG; obi:106868528; -.
DR OMA; KICYNGE; -.
DR OrthoDB; 3309149at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043067; P:regulation of programmed cell death; IEA:UniProt.
DR CDD; cd00022; BIR; 2.
DR CDD; cd16510; RING-HC_IAPs; 1.
DR CDD; cd14321; UBA_IAPs; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR048875; BIRC2-3-like_UBA.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10044:SF139; DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 2.
DR Pfam; PF21290; BIRC2-3-like_UBA; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00238; BIR; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 2.
DR PROSITE; PS01282; BIR_REPEAT_1; 1.
DR PROSITE; PS50143; BIR_REPEAT_2; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 341..376
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 289..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..307
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 44243 MW; E762DC8718D4D229 CRC64;
MELKSELNRI KSFCKWSTSY PLKPNDLAAN GLYHKGPEDN VCCVFCKCEI RNWKANDNIK
EKHRLVSPNC PFLCEDFVDN TPIPNKSDII FDRPKHPGLS LLIERLKTFS SWPKDKKQKP
EALAEAGFYH IGKADTVICF NCDGGLRNWK EDDIPWEEHA RWFPRCTFVQ QLKDSKYIGE
ANVKNRVSSL DSAMNSFSQD RPDSPFLQLD SIGRYFRMED NRRISDTSTS CSPELKYHKT
KTSCMETPKV KAVLSMGYKR NLVKRIVKNK IKETGSSFLQ ASDLLDAIEN NPHFDDDEEE
EEVSDEEEPD QTRAKHDTKM ASAARPDLIA ENNMLKEQKL CKICLDEELS VVFLPCGHLV
SCASCASALT NCPLCRKIIH GLVKIFF
//
