ID A0A0L8HUX1_OCTBM Unreviewed; 470 AA.
AC A0A0L8HUX1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Retinoid X receptor {ECO:0008006|Google:ProtNLM};
GN ORFNames=OCBIM_22005391mg {ECO:0000313|EMBL:KOF92999.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF92999.1};
RN [1] {ECO:0000313|EMBL:KOF92999.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF92999.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF92999.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR EMBL; KQ417249; KOF92999.1; -; Genomic_DNA.
DR RefSeq; XP_014769194.1; XM_014913708.1.
DR AlphaFoldDB; A0A0L8HUX1; -.
DR STRING; 37653.A0A0L8HUX1; -.
DR EnsemblMetazoa; Ocbimv22005391m; Ocbimv22005391m.p; Ocbimv22005391m.g.
DR EnsemblMetazoa; XM_014913708.1; XP_014769194.1; LOC106868437.
DR OMA; LEATICV; -.
DR OrthoDB; 5400963at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0003707; F:nuclear steroid receptor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06956; NR_DBD_RXR; 1.
DR CDD; cd06943; NR_LBD_RXR_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR000003; Retinoid-X_rcpt/HNF4.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24083:SF103; PROTEIN ULTRASPIRACLE; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00545; RETINOIDXR.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 132..207
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 243..466
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 52219 MW; 551F0009CD395FD3 CRC64;
MAHLPFGHYR NPDTLDSSMP SVSSMPLNSP PDIKPDISSL TPTSSHGHYF GFGHGMPPQM
PASVPSAMPS LPTSLHSNMS SLGSNHISSQ GHMHSPPLQS PPSSSLGSPP MMSLSPGSAS
SPPHMSGSFS SKHICAICGD RASGKHYGVY SCEGCKGFFK RTVRKDLTYA CRDDRNCIID
KRQRNRCQYC RYMKCLAMGM KREGVNFDVS RQGKERDFKA VQEERQRVKE KGEGEVESTS
SANVDMPVER ILEAELAVEP KIETYIDTQK DPVTNIFQAA EKQLFTLVEW AKRIPHFTKL
SLDDQVTLLR AGWNELLIAG FSHRSIPVKD GILLATGIHV HRSSAHHAGV GTIFDRVLSE
LVAKMREMKM DKSELGCLRA IVLFNPDAKG LVSTQEVESL REKVYASLEE YCKCQYPEET
GRFAKLLLRL PALRSIGLKC LEHLFFFKLI GDTPIDTFLM EMLETPSPQT
//
