ID   A0A0L8HZG3_OCTBM        Unreviewed;       696 AA.
AC   A0A0L8HZG3;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=OCBIM_22001385mg {ECO:0000313|EMBL:KOF94584.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF94584.1};
RN   [1] {ECO:0000313|EMBL:KOF94584.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF94584.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF94584.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; KQ416930; KOF94584.1; -; Genomic_DNA.
DR   RefSeq; XP_014768060.1; XM_014912574.1.
DR   AlphaFoldDB; A0A0L8HZG3; -.
DR   STRING; 37653.A0A0L8HZG3; -.
DR   EnsemblMetazoa; Ocbimv22001385m; Ocbimv22001385m.p; Ocbimv22001385m.g.
DR   EnsemblMetazoa; XM_014912574.1; XP_014768060.1; LOC106867644.
DR   GeneID; 106867644; -.
DR   KEGG; obi:106867644; -.
DR   OMA; FHEVMET; -.
DR   OrthoDB; 5488182at2759; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF136; ATP-DEPENDENT RNA HELICASE DHX35-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          60..225
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          257..433
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   696 AA;  78698 MW;  A6F45B5B2B62FA7F CRC64;
     MATFKPKFWR PGDEDPRSIL QEERVYESGE QYAVYNPYLS MTIQQQRQKL PVFALRTHIL
     YLVETYPVVV IVGHTGCGKS TQVPQYLLEA GWTGQRYKIA VCQPRRVAAV TLAKRVSEER
     GTMLGDEIGF HVRFDQCYDA ETTSIIFLTD GMLIREIFSD PLLTKYSVIM VDEAHERTQH
     TDILIGLLKK ILARRKDLRV IIASATLDAA EVKNFFNTNL TDNPKLDTAT ILSIEGRGYP
     VDIHYAIDPL PNYVQATVET ILKIHHNEVP GDILAFLTGQ DEVETVVHQL IQEARRMGQD
     VKMKMKVLRM YGSLPASEQL KVFDRTAKTT RKIVVATNIA ETSVTIHGIV FVVDCGFVKL
     RAYNAETGVE SLITVPISQA SADQRAGRAG RVRHGKTFRL YPESEYNKLS AATVPEIQRS
     ELSPVILQLK ALGVKNVLRF NFLSAPPAMN MLHSFELLYA LSALDEDGDL TTPLGMNMAE
     FPLSPMFAKM LLTAADFECT EEALTIASLM QIENVFVSPS NEKKAAERAK TKFSVHEGDH
     ITMVNVYNAF LEHNKSSQWC AENYLNLKGL NRACNIRNQL KQMLKKFKVQ LVSCGDNTEL
     LQRCIAAAFF ANAARLHYDG TYRTIRNNHC LHIHPTSVLY TDTPPQWVVF NEVIQTNKDY
     MRDITTIRPG WLCELAPHFF QFGTESEIAK KRAKFT
//