ID A0A0L8L185_9ACTN Unreviewed; 426 AA.
AC A0A0L8L185;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Serine protease {ECO:0000313|EMBL:KOG31819.1};
DE Flags: Fragment;
GN ORFNames=ADK37_29530 {ECO:0000313|EMBL:KOG31819.1};
OS Streptomyces resistomycificus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67356 {ECO:0000313|EMBL:KOG31819.1, ECO:0000313|Proteomes:UP000037251};
RN [1] {ECO:0000313|Proteomes:UP000037251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2290 {ECO:0000313|Proteomes:UP000037251};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG31819.1}.
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DR EMBL; LGUS01000191; KOG31819.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8L185; -.
DR PATRIC; fig|67356.5.peg.6310; -.
DR Proteomes; UP000037251; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR PANTHER; PTHR42884:SF14; NEUROENDOCRINE CONVERTASE 1; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF01483; P_proprotein; 3.
DR Pfam; PF00082; Peptidase_S8; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 3.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 2.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:KOG31819.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037251};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 74..207
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT DOMAIN 306..426
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT REGION 66..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOG31819.1"
SQ SEQUENCE 426 AA; 43942 MW; 0F69D1E689540992 CRC64;
ISSVLNGYDS KSGTSMAAPH VTGALAVLKQ TYPDKGIADL ESLLKTTGTT VTEADVSIPR
IDLGEAVGAT EPDPEPEPDP AARPLPSTII NDTDLVVPDP GTVESPITVS GFSGNAPGAL
QVSVNLAHDW LGEVKIDLVA PDGKAYALKA PNGTDPGGTL SKTYTVAAGA SPANGTWKLR
VQDRSAGAEG TLDNWSLTFP SHQNQADHTI PDAGSAESPI TVGGLTGSAP KTLQVYVDAT
HDWLGDLEIS LVAPDGRTYP LKSTSETEEG GTLQKLYTVD AGASPAGGTW KLRTEDASEG
ATGTLNGWSL TFPTSYENQT DHTVPDPGFV ESPITVSGLT GSASAATRVY VDATHDWLGD
LEISLVAPDG RTYPLKSTSE TEEGGTIQRL FTADAGASPA GGTWKLRAED ASEGATGTIN
GWSLAF
//
