ID A0A0L8L2L7_9ACTN Unreviewed; 403 AA.
AC A0A0L8L2L7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KOG32306.1};
GN ORFNames=ADK37_27890 {ECO:0000313|EMBL:KOG32306.1}, AQJ84_24830
GN {ECO:0000313|EMBL:KUN94610.1};
OS Streptomyces resistomycificus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67356 {ECO:0000313|EMBL:KOG32306.1, ECO:0000313|Proteomes:UP000037251};
RN [1] {ECO:0000313|EMBL:KOG32306.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 2290 {ECO:0000313|EMBL:KOG32306.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2290 {ECO:0000313|Proteomes:UP000037251};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KUN94610.1, ECO:0000313|Proteomes:UP000052992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40133 {ECO:0000313|EMBL:KUN94610.1,
RC ECO:0000313|Proteomes:UP000052992};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces resistomycificus DSM 40133, type
RT strain for the species Streptomyces resistomycificus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG32306.1}.
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DR EMBL; LGUS01000185; KOG32306.1; -; Genomic_DNA.
DR EMBL; LMWZ01000023; KUN94610.1; -; Genomic_DNA.
DR RefSeq; WP_053192411.1; NZ_LGUS01000185.1.
DR AlphaFoldDB; A0A0L8L2L7; -.
DR STRING; 67356.AQJ84_24830; -.
DR PATRIC; fig|67356.5.peg.5962; -.
DR eggNOG; COG1522; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR OrthoDB; 3523179at2; -.
DR Proteomes; UP000037251; Unassembled WGS sequence.
DR Proteomes; UP000052992; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037251}.
FT DOMAIN 16..66
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 403 AA; 40645 MW; C517860764C6654E CRC64;
MPASPSTARA INDRVALRLL QQEGPLTAGQ LKQLTGLSRP TVADLVERLI ASGLIAVVGE
SGEQRRGPNA KLYGIVADRA QLAALDVRTE GVAVLVSDLL GRVLAEASVP IGDDAGTGPA
VEQAVALVER VAKEAGADRL HTLGIGAPGL IDPVSGDLRD SSGLPEWHRQ LVAALQERFP
QARVSVENET NLAAVAEQRD GAARDRDTFV LLWLGVGIGA AVVLDGALRR GASGGAGEIG
FLPVPGTVGL PSATGCDGGF HSVAGAGAIA ALAAEHAVTA PSSAAEPHAA ALVRTAVEAV
ADAAPEADAA ADGFLDALAD RVALGAAAVI SVLDPGCVVL AGETGRAGGE VLARRVQERL
ARLSPLPTEV RASALGGQAV LRGALLTARD RAQDELFAPR GSG
//
