ID A0A0L8LGA4_9ACTN Unreviewed; 1236 AA.
AC A0A0L8LGA4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=HTH cro/C1-type domain-containing protein {ECO:0000259|PROSITE:PS50943};
GN ORFNames=ADK37_12055 {ECO:0000313|EMBL:KOG37140.1}, AQJ84_23775
GN {ECO:0000313|EMBL:KUN95091.1};
OS Streptomyces resistomycificus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67356 {ECO:0000313|EMBL:KOG37140.1, ECO:0000313|Proteomes:UP000037251};
RN [1] {ECO:0000313|EMBL:KOG37140.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 2290 {ECO:0000313|EMBL:KOG37140.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2290 {ECO:0000313|Proteomes:UP000037251};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KUN95091.1, ECO:0000313|Proteomes:UP000052992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40133 {ECO:0000313|EMBL:KUN95091.1,
RC ECO:0000313|Proteomes:UP000052992};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces resistomycificus DSM 40133, type
RT strain for the species Streptomyces resistomycificus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG37140.1}.
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DR EMBL; LGUS01000116; KOG37140.1; -; Genomic_DNA.
DR EMBL; LMWZ01000022; KUN95091.1; -; Genomic_DNA.
DR RefSeq; WP_053191015.1; NZ_LGUS01000116.1.
DR AlphaFoldDB; A0A0L8LGA4; -.
DR STRING; 67356.AQJ84_23775; -.
DR PATRIC; fig|67356.5.peg.2604; -.
DR eggNOG; COG1672; Bacteria.
DR eggNOG; COG2319; Bacteria.
DR OrthoDB; 134501at2; -.
DR Proteomes; UP000037251; Unassembled WGS sequence.
DR Proteomes; UP000052992; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR049052; nSTAND1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19879:SF1; CANNONBALL-RELATED; 1.
DR PANTHER; PTHR19879; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF20703; nSTAND1; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00530; HTH_XRE; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037251};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 22..77
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REPEAT 1071..1103
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1121..1162
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 1236 AA; 132084 MW; C8C8A5B359F5F033 CRC64;
MGRREKPVDP HAGPVQRLAH ELRLLREKAG KPPYREMAAR AGYSTTALSQ AAAGDQLPSL
AVVRAYARVL DADPDEWERY WREADAQVRA PSAEDRAPYR GLARYEPGDS DLFFGRDKQV
GELLELVRAR RFAAVFGPSG SGKSSLLRAG LIPVLRQAQG TDRPAVIRVV TPGERPSRTH
EEALVPKDGD LDTWVIVDQF EELFTLCHDR AERDRFLDLL LRARAPESRL RVAIAVRGDF
YGHCGAHPRL AEAVSRANLL VGPMNRDELR DAITGPATAE GLNVERVLTA RIIDEVTDQP
GSLPMVSHAL LETWRRRRGR TLTLAAYEEA GGVRGAIAGT AEQVYGELTP EQARIARRIL
LRLIAPGNGS ADTRRPASRA ELGPDAQDVL ERLAAARLVT LDGDTVELAH EVLITGWPRL
AGWIDESRER LRAQRMLGES ARAWEQLDRD AGALYRGARL TQAEELFARQ PHDDLAGPEQ
AFLDASRAAR DTEREAGNRA ARRTRLLSVG LSAFLVLALG AGLLAWQRDR ASDAEAAEAA
ARRLTTVADS LRTADPRTAA LLSVAAWRLA PLTDSRSALL DALARPERDA FTDPQTGENA
RRFLTDQGRA LITVTGAEAT VRDVAGHRVT ATYRLPGGTE VSDALDARSV VLMGQGGDEV
WDLAARKPAA ELGDAVHWAA PDGSAYATGP LEGPGPVRVY RTGDGKVVYT AHTPRSVTTA
AIGPGGRLLA LCPADGAPQV WDTVHGKRLP GAWEKAGGTV CGTGSGADGG LRLLRFSGDG
RRVAMVSGNT ATVWDVSDGR DVADFASGGT SGFTQADLSP DGRFLATADD REIAVWQLDQ
GGGQVFHAPL AGAEVGSLTW TPGRKRTLRY LDGATVRTYD LSDRLDARWQ STTADSTALS
PDGTTLATAT PSGSGYRFEL RSTATGAVLA RTRLGPLPAE TDDGHPQLAF SPDGRALAVA
DTVSSHGSLR QRFSVWDVPA HRVRTSFETS GATDRAVSAL ALGTGGRTLL VARSPSGDGT
AEVWDTSARR RTATLRALYA DRLALRPDGR LLAGSADRYA ELPSGRVSGV ALADGRQVTA
LAFSPDGTRL AVGDSTGHVT LWDGGLRHRM GILTGTSDTV SQGEPETVGA LAFSPDGDTL
AVGGNRGTLR LWDTAGQRLL GSDLPTSGTE IATLAFTRDG ATLYAGGPDV LLQRHPVAPD
DVVRTLCERA GAGLTRAQWR TYVPDAPYQQ VCPTAH
//
