ID A0A0L8LIT8_9ACTN Unreviewed; 475 AA.
AC A0A0L8LIT8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Multidrug transporter {ECO:0000313|EMBL:KOG38030.1};
GN ORFNames=ADK74_33895 {ECO:0000313|EMBL:KOG38030.1};
OS Streptomyces decoyicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=249567 {ECO:0000313|EMBL:KOG38030.1, ECO:0000313|Proteomes:UP000037606};
RN [1] {ECO:0000313|Proteomes:UP000037606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2666 {ECO:0000313|Proteomes:UP000037606};
RG Consortium for Microbial Forensics and Genomics (microFORGE);
RA Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA Blagden T., Winegar R.A.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG38030.1}.
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DR EMBL; LGUU01000283; KOG38030.1; -; Genomic_DNA.
DR RefSeq; WP_030078025.1; NZ_LGUU01000283.1.
DR AlphaFoldDB; A0A0L8LIT8; -.
DR PATRIC; fig|249567.6.peg.7451; -.
DR Proteomes; UP000037606; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13131; MATE_NorM_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 475 AA; 49397 MW; DB6BD29C997AD2FB CRC64;
MPAMQLTTLL RDSRALATLA VPLILTQLAQ VALTTTDTVM MGILGTADLA AGGLAIVLFN
QLRTMGVGLV TSVGNQIAAA SARAESAQDT GPGTARDESD DEVREIVRAS LAVATLAGIA
GAVLMLLIGQ TLTLLGQEAD VVARVQTMLL ALAPGLVPCL WFQAIRQFTV GMRRPQALLQ
ITIASVAVNA GINWVLIHGT WGLPKLGLPG VGVATTLVYL LSFLALYLSA KKDAVLAPLL
SLNIAKADRA TARRLVRLGI PIAATYGSEA GFFSVTALMA GSFGSAALAA HTAVNQLVYI
VFQVAVGLSH AASINVSREL ALGRTEAALR IKNTALACAG AVMVVVGIGY ITLPDLVLSP
FFDTSSARDA QAVSIATHLL LVIMVLQFFD CAQNIGVGLL RGLDDTKSGF RITLVGYWAI
GLPAAWLLGY AAGLHTLGIW LGLLTGLAAT AILLLRRYSA SLRAKFTAQQ AVPTA
//
