ID A0A0L8LKE5_9ACTN Unreviewed; 325 AA.
AC A0A0L8LKE5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KOG38574.1};
GN ORFNames=ADK37_09630 {ECO:0000313|EMBL:KOG38574.1}, AQJ84_06150
GN {ECO:0000313|EMBL:KUO00589.1};
OS Streptomyces resistomycificus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67356 {ECO:0000313|EMBL:KOG38574.1, ECO:0000313|Proteomes:UP000037251};
RN [1] {ECO:0000313|EMBL:KOG38574.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 2290 {ECO:0000313|EMBL:KOG38574.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2290 {ECO:0000313|Proteomes:UP000037251};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KUO00589.1, ECO:0000313|Proteomes:UP000052992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40133 {ECO:0000313|EMBL:KUO00589.1,
RC ECO:0000313|Proteomes:UP000052992};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces resistomycificus DSM 40133, type
RT strain for the species Streptomyces resistomycificus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG38574.1}.
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DR EMBL; LGUS01000083; KOG38574.1; -; Genomic_DNA.
DR EMBL; LMWZ01000003; KUO00589.1; -; Genomic_DNA.
DR RefSeq; WP_030041556.1; NZ_LGUS01000083.1.
DR AlphaFoldDB; A0A0L8LKE5; -.
DR STRING; 67356.AQJ84_06150; -.
DR PATRIC; fig|67356.5.peg.2087; -.
DR eggNOG; COG0604; Bacteria.
DR OrthoDB; 4190732at2; -.
DR Proteomes; UP000037251; Unassembled WGS sequence.
DR Proteomes; UP000052992; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08241; QOR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR43677:SF3; PROSTAGLANDIN REDUCTASE 3; 1.
DR PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037251}.
FT DOMAIN 11..315
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 325 AA; 33694 MW; C1D3228CBFAA1170 CRC64;
MQAWQVHENG EPSEVMRLED VARPTPGDGQ VLLKVRAANI NFPDVLMVRG HYQVRPPLPF
TPGVEICGET EDGRRVIANP ALPYGGFAEY AVADAAALLP APDALDDAQA AALHIGYQTG
WFGLHRRAGL EAGETLLVHA AAGGVGSAAV QLGKAAGARV IGVVGGADKA AVARDLGCDV
VVDRRAEDVI AAVKEATGGR GADVVYDPVG GEAYTQSTKV VAFEGRIVVV GFASGTIPGP
SLNHALVKNY SILGLHWGLY NTKNPKLVRH CHEQLTELAA RGAIKPLVSE RVPLREAAAA
VQRVGAGVTT GRLAVVPALT EGGAA
//
