ID A0A0L8LL50_9ACTN Unreviewed; 588 AA.
AC A0A0L8LL50;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:KOG38801.1};
GN ORFNames=ADK74_31540 {ECO:0000313|EMBL:KOG38801.1};
OS Streptomyces decoyicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=249567 {ECO:0000313|EMBL:KOG38801.1, ECO:0000313|Proteomes:UP000037606};
RN [1] {ECO:0000313|Proteomes:UP000037606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2666 {ECO:0000313|Proteomes:UP000037606};
RG Consortium for Microbial Forensics and Genomics (microFORGE);
RA Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA Blagden T., Winegar R.A.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG38801.1}.
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DR EMBL; LGUU01000271; KOG38801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8LL50; -.
DR PATRIC; fig|249567.6.peg.6947; -.
DR Proteomes; UP000037606; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 18..333
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 378..488
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 507..565
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 166
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 242
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 588 AA; 65564 MW; E8AD123DD5B6B8A1 CRC64;
MTLAQAESPR GLTIRGSEFL LDGEPFRILS GAFHYFRTHP KDWRDRLLRM RAMGLNTVET
YVAWNFHQPY EEKLDFTGWR DVASFVRTAD EVGLKVIVRP GPYICAEWDF GGLPAWLLKD
KDAPLRRSDP AYERTVDAWF AELLPRFVDL QATRGGPIIA MQVENEYGSY DDDHAHLEHL
RDTMRAQGVD SLLFCSNGAT QEALKAGSLP DLLSTVNFAG DPTGPFAELR TFQPDKPLFC
TEFWDGWFDH WGEQHHTTDP AQTAADVEKL LEAGASINFY MAVGGTNFGW SAGANLSGSG
YQPTVTSYDY DSPISESGEL TEKFHKVRDV LAKYTTLSST PLPATPRRMP AQRVAVRESV
ALMDALDALS TPVRQTAPVH MEALGQPYGL IHYRTRVRGQ QGSKGLRVTG LGDRALVFGD
GKRIGTFDRN QPDHTVDFTV ADASSTLDLL VDPTGRVNFG RSFNDPKGIS GKVLLDDEEL
SDWEIRRLPL DNLSALTFGS GDIPTGPAFH RARIHVDNPA DGFLAFPGWD KGMVWLNGFA
LGRYWSLGPQ VTLYVPSHLW RRGRNELVVL EMERTGDRIE VRAEPDIG
//
