ID A0A0L8LR59_9ACTN Unreviewed; 363 AA.
AC A0A0L8LR59;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Mechanosensitive ion channel protein {ECO:0000313|EMBL:KOG40673.1};
GN ORFNames=ADK74_23305 {ECO:0000313|EMBL:KOG40673.1};
OS Streptomyces decoyicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=249567 {ECO:0000313|EMBL:KOG40673.1, ECO:0000313|Proteomes:UP000037606};
RN [1] {ECO:0000313|Proteomes:UP000037606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2666 {ECO:0000313|Proteomes:UP000037606};
RG Consortium for Microbial Forensics and Genomics (microFORGE);
RA Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA Blagden T., Winegar R.A.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG40673.1}.
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DR EMBL; LGUU01000242; KOG40673.1; -; Genomic_DNA.
DR RefSeq; WP_048829981.1; NZ_LGUU01000242.1.
DR AlphaFoldDB; A0A0L8LR59; -.
DR PATRIC; fig|249567.6.peg.5179; -.
DR Proteomes; UP000037606; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 179..245
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 337..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 39366 MW; 0884479BF04EE33C CRC64;
MEDVLRPVVV IGGAVLLTLI LVWLTDRALR RIDAAHPETP LWGLLRRCRI PLQVALCAAL
LRGSFGQAGL KSADKHAAGI GQALTLVLIA AAAWLVIRAA AAIVESSYSR YAASGRDAAR
VRRVRTQVTL IQRVVTAVVI VVAAASMLLT FPEMRAVGTS MLASAGLLGI VAGIAAQSTL
GNLFAGLQIA FGDMVRIGDT VVVDGEWGTV EEITLTFLTV RTWDERRITM PVSYFTGKPF
ENWSRGGAQM TGTVFFHLDH GAPVEKMRQR LLEILQECPE WDGRSWSLVV TDTTPSTIVV
RALATARDAD TLWTVRCEVR ERMLEWLQAE HAYALPRIST SPAPTGTPLP DRGREPGPEA
ARG
//
