ID   A0A0L8MC94_9ACTN        Unreviewed;       363 AA.
AC   A0A0L8MC94;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:KOG47944.1};
DE            EC=1.1.1.262 {ECO:0000313|EMBL:KOG47944.1};
GN   Name=pdxA {ECO:0000313|EMBL:KOG47944.1};
GN   ORFNames=ADK74_09930 {ECO:0000313|EMBL:KOG47944.1};
OS   Streptomyces decoyicus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=249567 {ECO:0000313|EMBL:KOG47944.1, ECO:0000313|Proteomes:UP000037606};
RN   [1] {ECO:0000313|Proteomes:UP000037606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 2666 {ECO:0000313|Proteomes:UP000037606};
RG   Consortium for Microbial Forensics and Genomics (microFORGE);
RA   Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA   Blagden T., Winegar R.A.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOG47944.1}.
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DR   EMBL; LGUU01000092; KOG47944.1; -; Genomic_DNA.
DR   RefSeq; WP_048828889.1; NZ_LGUU01000092.1.
DR   AlphaFoldDB; A0A0L8MC94; -.
DR   PATRIC; fig|249567.6.peg.2139; -.
DR   Proteomes; UP000037606; Unassembled WGS sequence.
DR   GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR005255; PdxA_fam.
DR   NCBIfam; TIGR00557; pdxA; 1.
DR   PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF04166; PdxA; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:KOG47944.1}.
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   363 AA;  37322 MW;  A3EDCF93164AF78C CRC64;
     MTHPQQATDD RTAVTGRPAS DGPLPLLAVT LGDPVGIGPE ITARTLADPA TTALGRGLAV
     GDAAVLRRAV AVCGLDVEVN AVGTPGEARF EPGTIDVLDL GIAPADLPWG TVDAVAGRSA
     VAAIEAATRA ALAGEVDGVV TSPVNKEAIW AAGSQHLGHT EMLGELTGAA HFDTMFVVRG
     LKIFFTTRHL ALRKALDQIT EERVAASIRH AATALRVFGH DEPRLAVAAI NPHGGEGGHF
     GDEEITVLRP AVEKAAAEGL GVVGPIPADS VFHQGLEGRF DGVLSHFHDQ GHIPAKTVDF
     DGTVSVTVGL PILRTSVDHG TAFDIAGSGR ASHGTMAAAF RAAAGFSRFT DRIRAAYGTA
     AAR
//