ID A0A0L9T8Z1_PHAAN Unreviewed; 712 AA.
AC A0A0L9T8Z1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=LR48_Vigan352s001600 {ECO:0000313|EMBL:KOM27022.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM27022.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000256|ARBA:ARBA00038341}.
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DR EMBL; KQ258357; KOM27022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L9T8Z1; -.
DR STRING; 3914.A0A0L9T8Z1; -.
DR EnsemblPlants; KOM27022; KOM27022; LR48_Vigan352s001600.
DR Gramene; KOM27022; KOM27022; LR48_Vigan352s001600.
DR OMA; AYTTIHE; -.
DR Proteomes; UP000053144; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 2.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF110; CATION_H+ EXCHANGER 3; 1.
DR Pfam; PF00999; Na_H_Exchanger; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 99..214
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 242..328
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 712 AA; 78288 MW; AACF156E0B001806 CRC64;
MTVVVLSKGN GGALQQQRWR SPTAAVALSN GSGDVPRGSP TTVVEFSYGS GDASTVSVTL
SNVNGGALQR QWWRSPMAAV TVWEDGCTRV KNGCKGVNGI VNVEILSHIG LIYYAFLSGL
EMNLNTILNV NKKAASIAIA GIVFPILVAP CLYALFRKVY GHNMMFPLEE NTNNAYILWT
LILIVTSFPV VAHTLSELKL IYTGLGKEAL TATMIAVECF LVTTSLGCTN ACRYTDSYSP
DESWPFIVVI ILLLCALKIL GTLFVTFFFG MRIRDGLTLD MILNNKGAMA LIMLNIAWDR
TIFSLPTYAV ITSAVLLSTI VVSPVINAIY KTRQIFEQNK LKTIQKLRLN AELRFIACVH
NTRQATSMIS IIECFNPMRV SPVHVFALYL VELTGRVAAL VVTHIGKPSS QLREQNLTKS
QEELESIHNT FDALGEAYNA IRVETLNVVS AYTTIHEDIY HLAYEKRTTL ILLPFHKQLT
LEGTLEVTSV VYKDINQNVM KGAPCSVGIF VDRDFGLVPK MNLHICVVFV GGPDDREALA
IAWRMAGRSG TQLSLVRILL LGEAAEIDAS VHNESQGILS TIIDTDKQKE LDEEYISAFR
LITVNNSDTI SYSEIDVYSD KDIPVVLKEI EKIGCDIYIV GQGNCRNSKV FSNLFEGCEC
LELGVIGDIL VSNNFGSRSS VLVVQQYGYG GMVYGNNLNH KATDKGTFES IV
//
