ID A0A0L9TY91_PHAAN Unreviewed; 577 AA.
AC A0A0L9TY91;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 03-MAY-2023, entry version 24.
DE RecName: Full=Solute carrier family 40 member {ECO:0000256|RuleBase:RU365065};
GN ORFNames=LR48_Vigan02g160600 {ECO:0000313|EMBL:KOM35456.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM35456.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000256|RuleBase:RU365065}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365065}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365065}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279,
CC ECO:0000256|RuleBase:RU365065}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365065}.
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DR EMBL; CM003372; KOM35456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L9TY91; -.
DR STRING; 3914.A0A0L9TY91; -.
DR EnsemblPlants; KOM35456; KOM35456; LR48_Vigan02g160600.
DR Gramene; KOM35456; KOM35456; LR48_Vigan02g160600.
DR OMA; WTGSISQ; -.
DR Proteomes; UP000053144; Chromosome 2.
DR GO; GO:0009941; C:chloroplast envelope; IEA:EnsemblPlants.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:EnsemblPlants.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; SOLUTE CARRIER FAMILY 40 MEMBER; 1.
DR PANTHER; PTHR11660:SF53; SOLUTE CARRIER FAMILY 40 MEMBER 3, CHLOROPLASTIC; 1.
DR Pfam; PF06963; FPN1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU365065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365065};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365065};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365065};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365065}.
FT TRANSMEM 168..194
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 215..239
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 290..312
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 403..422
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 461..478
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 498..519
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 526..549
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
SQ SEQUENCE 577 AA; 62275 MW; B55C9A452EA574AF CRC64;
MAIAAASLTF HFAKFPIRQT NSFSIRHRIP SGRGFNLYYP RASHRFARFG FKCSLTDTDV
HLDHVTTDED DGQGRGVVEP LCPVPFVNLK TDILETDSLN LLAEATFVDT LLTTLPVLSE
EEQHALSATP AHPVGLHAFY ASCIAANVVE QLWNFAWPSA IALIHPSLLP VAVMGFFTKV
TIIVGGPLAA AQLLSSAMII HAHSVRHTSL SSLLLRPWFF ILVSVGAIER LCGVALGVAN
ERDWVVLLAG VNRPIALAQA NAVLNRIDLL CEIAGALLFG FLLSKFHPVI CLKVASGLMM
GLLPVTIIFT YLTNKLSTGV LDRPKPSQTC CRTFIEDSGT DAKSIVFKGL EAIKLGWKEY
LGQPVLPASL AWVLLYFNVV LTPGSLLTAF LTQRGLHPSI IGGFSGMCAV MGVAATFVSS
TLVEQFGILK AGAVGLVFQA LLLSMAVAVY LSGSISHQSP LLTFLFLIIL SRLGHMSYDV
VGAQIIQTGI PSSKANLIGT TEIAVASLAE SIMLGVAIIA NDPSHFGCLA LLSLLSVIGA
AWMFCRWLLN PTDEQKNLFS YDPQFEKYVS IPCTYHL
//
