ID A0A0L9UHU7_PHAAN Unreviewed; 770 AA.
AC A0A0L9UHU7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0000256|PIRNR:PIRNR017209};
GN ORFNames=HKW66_Vig0097390 {ECO:0000313|EMBL:KAG2400407.1},
GN LR48_Vigan04g232200 {ECO:0000313|EMBL:KOM42124.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM42124.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
RN [2] {ECO:0000313|EMBL:KOM42124.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:KOM42124.1};
RA Chooi Y.-H.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2400407.1, ECO:0000313|Proteomes:UP000743370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG2400407.1};
RA Xiang H.;
RT "Vigna angularis (adzuki bean) Var. LongXiaoDou No. 4 denovo assembly.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|PIRNR:PIRNR017209}.
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DR EMBL; JABFOF010000004; KAG2400407.1; -; Genomic_DNA.
DR EMBL; CM003374; KOM42124.1; -; Genomic_DNA.
DR RefSeq; XP_017422300.1; XM_017566811.1.
DR AlphaFoldDB; A0A0L9UHU7; -.
DR STRING; 3914.A0A0L9UHU7; -.
DR EnsemblPlants; KOM42124; KOM42124; LR48_Vigan04g232200.
DR GeneID; 108331843; -.
DR Gramene; KOM42124; KOM42124; LR48_Vigan04g232200.
DR KEGG; var:108331843; -.
DR OMA; YNTPLET; -.
DR OrthoDB; 11155at2759; -.
DR Proteomes; UP000053144; Chromosome 4.
DR Proteomes; UP000743370; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31618:SF20; MECHANOSENSITIVE ION CHANNEL PROTEIN 10; 1.
DR PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF017209; Memb_At2g17000_prd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR017209};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 588..654
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 29..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 87620 MW; EE69C75A4183A18F CRC64;
MDANFKKQGL QGGDVSLAEK KREVMVAIPN EGGGESLMPK QQSRGNSPHR MLNDEFSVKS
PPLNCASPEI RFMPSPNKPP KIPVSSANLT RRKSLTRSVY SKPKSRFGEQ PYPVDGTLLE
ENGTSTLQEN LGVGSPYKAS PINNKPGTIS RTVSILSVIT PKTPLMASPG PAGGEDFDEL
IYRKVELSKS KRSRRVTVKV LSEWFVFVCI TSTLVASLTV GKLKRTEIWG LGIWRWCVLV
MVTFCGMLVT RWFMRIIVFL IETNFLLRKK VLYFVHGLKK CVQFFIWLGL VLLTWVLLIN
RGVDRSELAT KILNGVTWTL ASLLIGAFLW FMKTLLLKIL ASNFHVKSFF DRIQETLFHQ
YILQTLSGPP LVEEAEKIGK SISVGHFSFR STDGKGGMKK ETIDIAKLHH MKQEKVSAWT
MKVLVDAMTN SRLSTISSAL DESFDDGENE QTDKEITNEM EATAAAYHIF RNVAPPGCTY
IDEEELRRFM IKEEVRMVYP LLAEAETGQI TRKSLTDWLL KVYQERKALA HALSDTKTAV
RQLNKLVTVI LVVVTVIVWL LLMEIATTKV LVFLSSQLVL AAFMFGNTCK NIFEAIIFVF
VMHPFDVGDR CVVDGVELLV EEMNILTTVF LKLNNEKVYY PNSVLAMKPI SNYYRSPDMG
DRVEFSIDFT TPAEKIGALR ERVKRYLERN PQYWHPNHGL VVKEIEDVNK IKMGIYVTHT
MNFQEFGEKN KRRTELVMEI KKIFEELNIR YNLLPQAIHL RHMEPDPRVT
//
