ID A0A0L9V8G4_PHAAN Unreviewed; 421 AA.
AC A0A0L9V8G4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN ORFNames=LR48_Vigan09g002000 {ECO:0000313|EMBL:KOM51361.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM51361.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CM003379; KOM51361.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L9V8G4; -.
DR STRING; 3914.A0A0L9V8G4; -.
DR EnsemblPlants; KOM51361; KOM51361; LR48_Vigan09g002000.
DR Gramene; KOM51361; KOM51361; LR48_Vigan09g002000.
DR OMA; RHQGYPC; -.
DR Proteomes; UP000053144; Chromosome 9.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF137; LIPASE; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..421
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005596342"
FT DOMAIN 46..102
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 177
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 364
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 397
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 421 AA; 46959 MW; 195E39E8F2D5D314 CRC64;
MANSVVSLVS IALLFLTTTQ GKTNFHGIPS SVTDHDFHVD GICETAVKTK GYQCEEHKVE
TDDGYILSLQ RLPAGRSGHK ADKPPVLLQH GLFCDALSWL INPPDEALGF ILADYGYDVW
ISNTRGTKYS RSHRSLSPND AAFWNWSWDE LASYDLPAFV KYVHNNTAQK IHYVGHSLGT
LMAFTAFSRG QVLDRLRSAA LLSPIAHMRQ VNSPIARVFA DTFLAEHLNF IGIHEFIPNG
EMIPSVVAKT LDLVMSREGS TRLVEGICKI LRIDCSKPLA YFTGPNCCLN STLLNSLLDH
GLQSTATKNL IHLGQMIRTG NIAKYDYGNF LKNTENYGQP LPPPYDFTAI PKEFPLFLSY
GGLDMLSEVN GVNLLLNDLK SHDANKLVVL LRKEYAHVDF FMATNVKQVL YDPIISFFED
N
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