ID A0A0L9VSB2_PHAAN Unreviewed; 459 AA.
AC A0A0L9VSB2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Solute carrier family 40 member {ECO:0000256|RuleBase:RU365065};
GN ORFNames=LR48_Vigan11g097400 {ECO:0000313|EMBL:KOM57941.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM57941.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000256|RuleBase:RU365065}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365065}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365065}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279,
CC ECO:0000256|RuleBase:RU365065}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365065}.
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DR EMBL; CM003381; KOM57941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L9VSB2; -.
DR EnsemblPlants; KOM57941; KOM57941; LR48_Vigan11g097400.
DR Gramene; KOM57941; KOM57941; LR48_Vigan11g097400.
DR OMA; YPVFISY; -.
DR Proteomes; UP000053144; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; SOLUTE CARRIER FAMILY 40 MEMBER; 1.
DR PANTHER; PTHR11660:SF57; SOLUTE CARRIER FAMILY 40 PROTEIN; 1.
DR Pfam; PF06963; FPN1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU365065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365065};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365065};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365065};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365065}.
FT TRANSMEM 56..77
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 89..113
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 125..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 183..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 330..354
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
SQ SEQUENCE 459 AA; 51220 MW; A3BA57DE03A8D294 CRC64;
MEESVKLRVP PLTGQQEQPL ALINYLYIGH FLARWGTRMW EFSVGLYMIN IWPESLLYAA
IYGAVESASI AVCGPIIGRW VDKLSSLKVL QLWLVTQNLS FVIAGASVVA LLIHSSLKFT
HFSIFMLLVL LINVCGGIGV LSTLAGTILI EREWLLVISE DQPPELLTKM NSVTRGIDLC
CKLLAPVITG FIISFVSLKA SAITLALWNT VSVWVEYWLF TSVYEGIPAL GQSSQKRMAR
FLQCDQEMNN LTSEEDSLLP ITECSSELAG RKWNKNISEK ISEIPYIAAW RVYLQQEVAL
PGLALALLFF TVLSFGTLMT ATLEWEGIPA YVIGLGRGIN AVIGIAATVV YPVLQSRIST
VRTGLWSIWS QDLVAESDRL IVGGVQNSLQ SLMELLAYVM GIIISDPRDF WKLAVISFQA
VTLAAFLYCI HSYHVRKHLF HFDRMLWAKC FRRASQVAS
//
