ID A0A0M0BE20_9ARCH Unreviewed; 376 AA.
AC A0A0M0BE20;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369, ECO:0000256|RuleBase:RU000441};
DE EC=2.3.3.16 {ECO:0000256|PIRNR:PIRNR001369};
GN ORFNames=AC481_06825 {ECO:0000313|EMBL:KON26604.1};
OS miscellaneous Crenarchaeota group archaeon SMTZ-80.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=1685135 {ECO:0000313|EMBL:KON26604.1, ECO:0000313|Proteomes:UP000037599};
RN [1] {ECO:0000313|EMBL:KON26604.1, ECO:0000313|Proteomes:UP000037599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SMTZ-80 {ECO:0000313|EMBL:KON26604.1};
RA Lazar C.S., Baker B.J., Seitz K.W., Hyde A.S., Dick G.J., Hinrichs K.-U.,
RA Teske A.P.;
RT "New insights into the roles of widespread benthic archaea in carbon and
RT nitrogen cycling.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|PIRNR:PIRNR001369};
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU000441}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KON26604.1}.
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DR EMBL; LFWY01000044; KON26604.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0BE20; -.
DR PATRIC; fig|1685135.3.peg.321; -.
DR Proteomes; UP000037599; Unassembled WGS sequence.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 262
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 313
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 376 AA; 42727 MW; 0A2353ECB73537BC CRC64;
MQESQEEIKR GLKDVVACET RISYVDPKGQ LYYAGYNTDV LAGRVSFAEA VYLTWFDNLP
SQKELSDFES TILSEMSLPE SVIKRLKSYS NGNHPMDILQ SEIPHLGMHD PDLGDNSDSA
NRKKAIRIVA KVPTIVANLN RIRNNEPLIP PDDKLDFASN FLYMFLGKYP DELERETINK
YMYLHLDHGL AASTFVARST VSTQSDMYSG VASALGSLKG KFHGGANERV RGMLNEIKNL
GDVEAYIQGR LDVKKRIMGF GHRIYQADDP RTKHLRELCE NLCRRANKLD LYEKSKEIEY
VVLNKKNIRP NVDFYAATIL DALGIPVTFS TPFFASSRVA GWIAHIIEEL SQRIIMRPTS
RYTGKYGREF IPIDKR
//
