ID A0A0M0BIH4_9ARCH Unreviewed; 718 AA.
AC A0A0M0BIH4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=AC481_01600 {ECO:0000313|EMBL:KON28422.1};
OS miscellaneous Crenarchaeota group archaeon SMTZ-80.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=1685135 {ECO:0000313|EMBL:KON28422.1, ECO:0000313|Proteomes:UP000037599};
RN [1] {ECO:0000313|EMBL:KON28422.1, ECO:0000313|Proteomes:UP000037599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SMTZ-80 {ECO:0000313|EMBL:KON28422.1};
RA Lazar C.S., Baker B.J., Seitz K.W., Hyde A.S., Dick G.J., Hinrichs K.-U.,
RA Teske A.P.;
RT "New insights into the roles of widespread benthic archaea in carbon and
RT nitrogen cycling.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KON28422.1}.
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DR EMBL; LFWY01000005; KON28422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0BIH4; -.
DR PATRIC; fig|1685135.3.peg.1349; -.
DR Proteomes; UP000037599; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00028; TPR; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 345..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 461..593
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REPEAT 654..687
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 718 AA; 81571 MW; 7C9831D03F4B5F38 CRC64;
MKKFKHKENA LISISIALAA IIISLFLAQI TTFRNLELDL LDYRFNIRGP LDVSNSPIVI
LAIDDQSDGS TPHRWPWPRE YFAHVIENLN EAGAKVIGVD VIFEQADIHG PESDNKFADV
LSKFNNVVLA GKIHVPSGRT DIVTLVPPYE KFIAQGTLWG LVSFDLDEDG FYRRYLVGQN
YNDAVYNSFA AEVMKVYMNL DRNLRVANLE DIFKIGPFTI PKFDGYSTLI NYSGPAGTFQ
MYSFDNVLDD VDFDLLDEFD IDSFDDPGDT ELGLPPGLLY SGVLQDKIVL IGSTMQELHD
EFNSPFLEVR DSEGRISKIL TPGVEIHANA LNMILTDNYL HNVPYFGHLT ILILLALLAF
LITRSLRTFL GALTIAIVVV IYFAAAFVVF SYWNLVVDII TPILVILFSY VGHTLYHYIL
SQQEKRMIRG AFSHYVPEKV VAEILENPEK LTLGGEERVV TVMFSDVVGF TTISERLTPA
ELVQLLNEYL TEMTDIILQH QGIIDKYEGD AIMAEFGVPV PYENHPYMAC IAALEMQEKL
NVLRNKWKDE GKPLLKARIG INTGEVIIGN MGSRDVFDYT VMGDHVNLGS RLEGANKFYG
TEIMLSEFTY DYIKDGFYTR ELDLIRVKGK EKPIRVFELI ATKKIQLDEK FIEMLDIYRK
GLENYKAQDW DQAIDCFETC LKLRPNDTPS SEYRSRCIEY KFNSPGPDWD GVTVMKEK
//
