ID A0A0M0BYZ0_9ARCH Unreviewed; 592 AA.
AC A0A0M0BYZ0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=alanine--tRNA ligase {ECO:0000256|ARBA:ARBA00013168};
DE EC=6.1.1.7 {ECO:0000256|ARBA:ARBA00013168};
GN ORFNames=AC477_01290 {ECO:0000313|EMBL:KON33669.1};
OS miscellaneous Crenarchaeota group-1 archaeon SG8-32-1.
OC Archaea; Candidatus Bathyarchaeota; MCG-1.
OX NCBI_TaxID=1685124 {ECO:0000313|EMBL:KON33669.1, ECO:0000313|Proteomes:UP000037237};
RN [1] {ECO:0000313|EMBL:KON33669.1, ECO:0000313|Proteomes:UP000037237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8-32-1 {ECO:0000313|EMBL:KON33669.1};
RA Lazar C.S., Baker B.J., Seitz K.W., Hyde A.S., Dick G.J., Hinrichs K.-U.,
RA Teske A.P.;
RT "New insights into the roles of widespread benthic archaea in carbon and
RT nitrogen cycling.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KON33669.1}.
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DR EMBL; LFWU01000024; KON33669.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0BYZ0; -.
DR PATRIC; fig|1685124.3.peg.180; -.
DR Proteomes; UP000037237; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00673; AlaRS_core; 1.
DR Gene3D; 3.30.54.20; -; 1.
DR HAMAP; MF_00036_B; Ala_tRNA_synth_B; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002318; Ala-tRNA-lgiase_IIc.
DR InterPro; IPR018162; Ala-tRNA-ligase_IIc_anticod-bd.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018164; Ala-tRNA-synth_IIc_N.
DR InterPro; IPR023033; Ala_tRNA_ligase_euk/bac.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR012947; tRNA_SAD.
DR PANTHER; PTHR11777:SF9; ALANINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR11777; ALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01411; tRNA-synt_2c; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR PRINTS; PR00980; TRNASYNTHALA.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF101353; Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS); 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KON33669.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 3..592
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 592 AA; 67077 MW; 08CD01183AEFCDA3 CRC64;
MVINSKKLKK LFLDFFSAKE HNLIPNSPLI PEYDPTVLFT PAGMHPLIPY FLGQPHPLGR
KLVNVQRCFR AGDIECVGDS SHLTFFEMLG SWSLGDYFKK QAISLSYEFL TNKRWLNLDK
KRLYVTVFAG DKDSSKDDES FTVWNSLGLP DDHIFFLSNE DNWWGPVGNT GPCGPCTEMF
YDTGKPLCSS SCKPGCSCGK YFELWNDVFM EYNKTHTGFY ELLKQKNVDT GMGVEHTAAM
LEGKNHVFEI DAILPIAKTV KELASITVPT PTEERSIRII TDHIRASTFF LGDERGVKPS
NLDRGYVLRR LIRRAIRFGR LIGIKKDFLS YIAADVITIN ESEYPLLREK QASIFEELTK
EETKFKNTLE KGLRKFQRIA ENSPKIDGKN AFLLFQSFGF PIELTKELAS EIGADVDEIE
FRNEYERHQK VSGASAKKLF KGGLSDASTQ TKKLHTATHL LNEALRVVLK NKDIVQRGSN
ITPERLRFDF NFDRPLKPEE IVAVEKLVNE QILKCLPVIR EEMTVDEAKS KGAQAVFDEK
YSNKVSVYKV GDFSTEICGG PHVSNTSELG IFKITKQKGI AAGVRRIRAT LK
//
