ID A0A0M0G5T2_9BACI Unreviewed; 401 AA.
AC A0A0M0G5T2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Beta-ketoadipyl CoA thiolase {ECO:0000313|EMBL:KON85235.1};
GN ORFNames=AF331_14835 {ECO:0000313|EMBL:KON85235.1};
OS Rossellomorea marisflavi.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Rossellomorea.
OX NCBI_TaxID=189381 {ECO:0000313|EMBL:KON85235.1, ECO:0000313|Proteomes:UP000037405};
RN [1] {ECO:0000313|Proteomes:UP000037405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 11544 {ECO:0000313|Proteomes:UP000037405};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Fjat-14235 jcm11544.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KON85235.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGUE01000004; KON85235.1; -; Genomic_DNA.
DR RefSeq; WP_053428832.1; NZ_LGUE01000004.1.
DR AlphaFoldDB; A0A0M0G5T2; -.
DR STRING; 189381.GCA_900166615_00942; -.
DR GeneID; 42293209; -.
DR PATRIC; fig|189381.12.peg.3055; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000037405; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF2; 3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000037405};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 4..268
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 276..398
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 355
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 385
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 401 AA; 42671 MW; 169B7995BDB752DD CRC64;
MREVVIVDAV RTPIGRYKGS LKGVRPDDLG AVVIKALIAR NPDVPPEAIE EVVFGNANGA
GEDNRNVARM SALLAGLPVE VGGTTINRLC GSGLDAVNYA ARAILAGEGE IFIAGGTESM
TRAPLVMRKP EGEFPRGNME LFDTTIGWRF VNPKMEDMYG TDSMPETAEN VAKKFNISRE
EQDRFALGSQ TKAREAQVHG RLDYEIVSVE VLHKRNETMR VTQDEHPRPE TDLAKLAGLK
PLFKGGTVTA GNASGVNDGA AALLLMSRGK AEELGLTPLA RYVTSAVAGV EPSVMGIGPI
EATRKALTRA GITMEQLGLV ELNEAFAAQS LACIRELGLD EAIVNVNGGA IAYGHPLGAS
GARILTTLLH EMKRRDVQYG LATMCIGVGQ GIATVVERLK G
//
