ID A0A0M0GI31_SPOGL Unreviewed; 397 AA.
AC A0A0M0GI31;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Acetyl-CoA acetyltransferase {ECO:0000256|ARBA:ARBA00044137};
DE EC=2.3.1.9 {ECO:0000256|ARBA:ARBA00012705};
DE AltName: Full=Acetoacetyl-CoA thiolase {ECO:0000256|ARBA:ARBA00030755};
GN ORFNames=AF332_23510 {ECO:0000313|EMBL:KON89494.1};
OS Sporosarcina globispora (Bacillus globisporus).
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Sporosarcina.
OX NCBI_TaxID=1459 {ECO:0000313|EMBL:KON89494.1, ECO:0000313|Proteomes:UP000037109};
RN [1] {ECO:0000313|Proteomes:UP000037109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4 {ECO:0000313|Proteomes:UP000037109};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Fjat-10036 dsm4.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KON89494.1}.
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DR EMBL; LGUF01000007; KON89494.1; -; Genomic_DNA.
DR RefSeq; WP_053436860.1; NZ_LGUF01000007.1.
DR AlphaFoldDB; A0A0M0GI31; -.
DR STRING; 1459.AF332_23510; -.
DR PATRIC; fig|1459.3.peg.5186; -.
DR OrthoDB; 2774224at2; -.
DR Proteomes; UP000037109; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KON89494.1};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KON89494.1}.
FT DOMAIN 9..266
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 273..394
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 93
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 352
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 382
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 397 AA; 42418 MW; 06631802AD555662 CRC64;
MRWIRKRNVV ITSAVRTPIG TFGGAFKDLL PTDLIVPVLK EAAERSGLQS DEVDEVILGH
CIQRTDEPNT ARTAALLAGF DDTTTGFTVQ RQCASGMQAI ISAALQIQSG MSDIVIAGGV
EAMSSSPYVL KQHRWGARMQ HGQITDTVWE ILEDPIHHIM MGETAENLAE IHSITREEQD
EAALLSHQRA LHAIENGYFD SQIVPITVKS RKGEVTVTKD ENPREDLTAE KLGSLKPVFR
KGGSVTAGNA SSLNDGGAAL VLMPEELALE KGLKPMAKIV GCSVAGVDPK VMGRGPVPAV
KKGLANVNWL LEDADLIEVN EAFAAQYLAV EKELGLSRDK VNVSGSGISL GHPIGCTGAR
LVVSLVHELK RRGGRKGIAS LCVGGGMGAT VFVETYE
//
