ID A0A0M0JET4_9EUKA Unreviewed; 771 AA.
AC A0A0M0JET4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=Phosphatidylinositol-trisphosphate 3-phosphatase TPTe2-like protein {ECO:0000313|EMBL:KOO24753.1};
GN ORFNames=Ctob_003434 {ECO:0000313|EMBL:KOO24753.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO24753.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO24753.1}.
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DR EMBL; JWZX01003057; KOO24753.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0JET4; -.
DR OrthoDB; 5477362at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR029023; Tensin_phosphatase.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR12305; PHOSPHATASE WITH HOMOLOGY TO TENSIN; 1.
DR PANTHER; PTHR12305:SF60; PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51181; PPASE_TENSIN; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 253..429
FT /note="Phosphatase tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51181"
FT DOMAIN 340..408
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 433..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..622
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 84175 MW; 61F0813B9C28153E CRC64;
MPEVSIQIVE SRAPAPLKRF QEAGKSVMHS SSLTVVLPVS VLEDAQWPAM GPFDGRTQPP
KDEDEEAQLE ELRRKRQEKL EAVQALGGHA AGKRMTGRQR ARWMIEGWKW QLFLLVVAII
DIAMLFVELN AGPGAMIPVA VVTFVVLFIF VVDLIIRYYA FRNKLFSSFW FWFDFFVVAF
SIVLFLIGLG FGSTDAEVGQ SGSTAARGGK ALRGMIVALR WLRAARLVIK LTQVKGGAST
AARHATGENK KRYVDLEHGF DLDLAYVLPD LIAMSVPAIG WTALYRNPLP EVARFLELRH
GKGGYTIINC CPELPYPPDK FKSGEVVRFD IQDHTPPNML QFVSFLNSMR HKPASHTLAI
HCRGGKGRTG SMCCAWLLYS RACLDADDAL THFALERTEL SLGKKKIQGV DTPSQRRYVH
QLDALLRAQS AYLTEPTRRR RAPASTSDAQ GEESATSLRE ESSSSSSSCW SPDGTDGSCR
SPNGRPAGSL VRPPACPTAS MRSLDLVNWY AKAPKGALVC AVHRNGGEGE DRGKVVHWSP
PVRDFSTAGS LISFDLAGVD VDGDVRVSVF ALDDLLKVRR KRLKKGLAAR LPFDAAPTGP
WEDTADTPET AMRQKKSKKD DKRVIAGKES GCKFFLLFHT GFVSSTGEMP VPLKMMDKAF
KNKGKKYRPE GVATLRFELL EKASIKPTLG AAVDQAVGAH EAELSADPSA DSSTSSATRN
QGALARARKA SGASSSVETS AMPETTRPTG ESTALAEMMA AAEGDRSDDQ I
//
