ID A0A0M0K9T2_9EUKA Unreviewed; 1352 AA.
AC A0A0M0K9T2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Rcc1 repeat-containing protein {ECO:0000313|EMBL:KOO35362.1};
GN ORFNames=Ctob_005889 {ECO:0000313|EMBL:KOO35362.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO35362.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO35362.1}.
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DR EMBL; JWZX01000899; KOO35362.1; -; Genomic_DNA.
DR OrthoDB; 101036at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 5.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR22870:SF463; E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED; 1.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF00415; RCC1; 10.
DR Pfam; PF13540; RCC1_2; 1.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
DR PROSITE; PS00626; RCC1_2; 6.
DR PROSITE; PS50012; RCC1_3; 13.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 33..103
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 104..154
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 155..206
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 207..258
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 260..326
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 327..410
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 411..468
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 469..521
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 522..572
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 573..624
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 625..676
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 678..729
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 737..788
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 1012..1227
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 824..845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 880..910
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1352 AA; 147033 MW; BDC62DF158E5B3D7 CRC64;
MLQQQATRTR DTKTKKKFID AGLGHSLAVL ENGHLVAFGM ARNFQLGTDF IKEKERRNGK
TEAMLGEPQD EHYPKRLLAL EKEGDSIVTM AAGSSHSLAV TQQGHVYSWG SGAFGKLGHG
DEQNVRIPKA VEFKRKRIAR VACGSDHSAA ISEGGEVLTW GAGSYGNLGH GDNANVYSPK
IVEALLGKAC ISVACGSKHT IALTAAGSVY TWGYGGGGRL GSGDTRGMFR PKLVNDLKDQ
ACLMIAAGES HSMAITAEKA QCYTWGVGDY GKLGHGDTTP QLLPRHLEYF RNAQLIWCAG
GTFHSAACAQ PDVECGTFHT IALTKNGDLF TFGYNGNGRL GLGAQNDPSK SRTVPAHIKN
LEKVMSDRDD SGNFGSSGDA ADAAYKKALT PKYIRYLCFG GFYSVALSDQ GDVYTWGDGR
YGATGHDLSR LDEREVSRPM RVLSLGGHRK PVIQLAAGVR HVLAVTSDGT IYSWGDGTLG
RLGHGDQSKI EEPRIIATLK GHCQIIHAAA GEEHSAAVTS DGRLYTWGSG SFGKLGLGEP
EDETTPRLVP LDAKKVVMVA CAYAHSVALC AGYEVLAWGS GFKGKLGLSD DQNRLVPTEI
RLLRRKMVKE ICCGSFHTMA LTQTGDLYTW GIGERGQLGH GDLENRNAPK AIQHLQGIEI
GAIAAGEAHS LAATKDRMRV YAWGAGHYGQ LGVGGLDPRL TPTPIHDLEG QKVIHVACGA
NHSGAVALGA SEEAGMAKVF TWGNGANSRL GTGRIDEQDL PLEVVELSSS SLTSVSRDDE
PSRLLTPEMI RRLHGTDIDA ATAQKILDDS QTVAVRAAQV VDSGGGSGAL ATGSGEPSSG
EQADSTTIST VMAVAMAGRA IRPSLDVLQQ LVKSQTYNVA EVIENEQKQI EQLKAKLDEA
VVINEAAEAA CLEIENKVQL VLANHKTVHE TLCRYNAYQH RELMPGIKSS GFPKGLYERM
ISVLYLEPAN LSVMLKKVEE SEAALGKSEN DETNRLVAII CDRIYSNHYK ARDEYYILSL
IIHATNEDMA SVQEPRQILA SVNYVTKLMA AYTRRGPNIE ALKDMLFKPL AAVLSRKSLD
LEIDPARVYQ ACAQVLRHKI GEDLPEKLSS KEAWQFREVR EIIQPRVKTL VEIVELFLTR
VIACRNQLPY GIRVLAKRVY EMTQDRFPKA TDEQRMAGVA NFVFTTYLCP AIIQPEAFEL
CSASSRPTAA MKRNLLRIAT SLKAVGCLRH FDDNAEPWML ELSAKIKVST ELMKQFYSNL
ADVPELDEQR RITVYMESTE SRTPTRAFEL NSLYLVHSVL YRHHSEVVSS SENPLTAILL
ELGNMPDQVS SEQNKQVGAH AARRPVALAL VP
//
