ID A0A0M1JSG6_9CYAN Unreviewed; 433 AA.
AC A0A0M1JSG6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=AM228_17200 {ECO:0000313|EMBL:KOR35675.1};
OS Planktothricoides sp. SR001.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Planktothricoides.
OX NCBI_TaxID=1705388 {ECO:0000313|EMBL:KOR35675.1, ECO:0000313|Proteomes:UP000037054};
RN [1] {ECO:0000313|Proteomes:UP000037054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SR001 {ECO:0000313|Proteomes:UP000037054};
RA Tan B., Te S.H., Thompson J., Gin K.;
RT "Draft Genome of Planktothricoides sp. SR001.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOR35675.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIUQ01000029; KOR35675.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M1JSG6; -.
DR STRING; 1705388.AM228_17200; -.
DR PATRIC; fig|1705388.3.peg.154; -.
DR Proteomes; UP000037054; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000037054}.
FT DOMAIN 212..369
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 48316 MW; 872B5AFD7C0A7088 CRC64;
MWVPSPEAKS PPSSDRACLP PKNQPRIQAN MAVQSVDSVE AKSTEALCSA TPQESVALTF
PDSQRLLQQY DALSQHLQVV ENQKLQQVGL KLFWDQGMKL ATQATELGKN AGANVQSLQK
TKSLWQEAID TLSKIDPGSE YGDSASADRY ANRAREKIAS YQQNLADITY RLEVAQSDFL
AEIAQRSGLS NQAKITICHL QSHRCRRLRG NEYPRSAASL MKLPVAVAVM HKLTTENIRF
DTPIYVDPSN FTEDASEIGV GQKYPIETVL KEMIAKSSNI ATNQLIDYLG WDYINQVLAE
RGFKDMHIGF KMMGDRIMPS NPGHSRNLLT SDELTEMMMQ IYNRQHLGDE RLILALESQY
DRALGFAGIE SAIGNWLGEK TGQTSEVLGT TLAMNLFGET YIITVIDDGY YSEPTIRQVV
SEIAEYILRN GHL
//
