ID A0A0M1P0C1_9BACL Unreviewed; 396 AA.
AC A0A0M1P0C1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=acetyl-CoA C-acyltransferase {ECO:0000256|ARBA:ARBA00024073};
DE EC=2.3.1.16 {ECO:0000256|ARBA:ARBA00024073};
GN ORFNames=AM231_16715 {ECO:0000313|EMBL:KOR87554.1};
OS Paenibacillus solani.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1705565 {ECO:0000313|EMBL:KOR87554.1, ECO:0000313|Proteomes:UP000036932};
RN [1] {ECO:0000313|Proteomes:UP000036932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-22460 {ECO:0000313|Proteomes:UP000036932};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOR87554.1}.
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DR EMBL; LIUT01000002; KOR87554.1; -; Genomic_DNA.
DR RefSeq; WP_054403708.1; NZ_LIUT01000002.1.
DR AlphaFoldDB; A0A0M1P0C1; -.
DR PATRIC; fig|1705565.3.peg.240; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000036932; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF8; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KOR87554.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036932};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KOR87554.1}.
FT DOMAIN 5..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 396 AA; 40964 MW; 281A0D735F785A9A CRC64;
MREAVIVSLA RTPVGKAKKG SFAQTRAEDL GKAVLEAVIE RAPGLKKEDV EDIILGCAMP
EGEQGLNVAR IISLYAGYPV TVPALTVNRF CSSGLQAIAF AAERIMLGHA EVIVAGGVES
MSHVPMTGFK PAPHPTIVEE MSEVYIGMGH TAEEVARRFG ITREAQDAFA ASSHRKAAAA
IAEGKFRDEI VPVNVTLAAA DEQGKVRSST FTFDTDEGVR PDTTPEVLAK LKPAFALGGS
VTAGNASQTS DGAAAVAVMS REKADELGLT PLATFKSFAL AGVEPEIMGV GPVEAIPKAL
RMAGIELDQV DVFEINEAFA SQCLHIIRAL GIDESKVNVN GGAIALGHPL GCTGAKLTVS
LVSELARRGG GYGVVSMCIG GGMGAAGVFE VHAAGA
//
