ID A0A0M2GP28_9ACTN Unreviewed; 428 AA.
AC A0A0M2GP28;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Ion channel protein {ECO:0000313|EMBL:KJK37052.1};
GN ORFNames=UK15_23715 {ECO:0000313|EMBL:KJK37052.1};
OS Streptomyces variegatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK37052.1, ECO:0000313|Proteomes:UP000034786};
RN [1] {ECO:0000313|Proteomes:UP000034786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK37052.1}.
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DR EMBL; JYJH01000018; KJK37052.1; -; Genomic_DNA.
DR RefSeq; WP_031140330.1; NZ_JYJH01000018.1.
DR AlphaFoldDB; A0A0M2GP28; -.
DR STRING; 284040.UK15_23715; -.
DR PATRIC; fig|284040.3.peg.2679; -.
DR Proteomes; UP000034786; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF9; ION-TRANSPORT PROTEIN YFEO-RELATED; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 428 AA; 43569 MW; BF44CBE824D57A0C CRC64;
MVQDSAQQAP SVTPATPART LMPTILPALA VGILSSLVLV GVEVAAEELQ NVLWGPLPDA
LGIGRYSVAW MFVMLFATGV AVGLVVWKAP GHAGPDPATI GLDAPVLPPV VLPGLLLVTA
LMLAGGPSLG PENPVITVNV ALAAWLGARL VPRAPGRVWP ALAEAATIGA LFGTPVAAAL
VISEALAGKE TRGLLWDNVF APLTAATAGA LTATLIDHPS FDLDLPSFGR PDWSDLLAAA
VVAAVAAVLG MAAVRAFPYV HGVFRRLRHP MLMLPAGGLV LGALAALGGH LTLFKGLEEI
AELARDPDSR SAGEYALLTV VKLAALLVAA SCGFRGGRIF PAVFAGTALG LGAHALVPGV
HPSIGVSAAV LGLLLAITRQ GWVSLFVAAV LVASPAIIAV LCVASLPAWL LVTGRPQMQL
RPDGTPVR
//
