ID   A0A0M2GPB4_9ACTN        Unreviewed;       242 AA.
AC   A0A0M2GPB4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KJK37142.1};
GN   ORFNames=UK15_24070 {ECO:0000313|EMBL:KJK37142.1};
OS   Streptomyces variegatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK37142.1, ECO:0000313|Proteomes:UP000034786};
RN   [1] {ECO:0000313|Proteomes:UP000034786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJK37142.1}.
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DR   EMBL; JYJH01000018; KJK37142.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M2GPB4; -.
DR   STRING; 284040.UK15_24070; -.
DR   PATRIC; fig|284040.3.peg.2750; -.
DR   Proteomes; UP000034786; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR24567:SF79; CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR CRP; 1.
DR   PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
FT   DOMAIN          17..137
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          151..228
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51063"
SQ   SEQUENCE   242 AA;  26639 MW;  BAF1D87EDB458384 CRC64;
     MRPSEVLVNH AWPPSTFLGR LRNATREELL TQGTPIAYPP HRALLQQGDE SRHILLITSG
     VVKVVASAES GYDMLLAVRI AGDLVGEMAA FEERPRSGTV VACSDVTARI IQMRALETFL
     TRHPDAMRAI LHMLCARLRW ANRRRVDFQA YDSMTRLARV LAELSQAYAQ PAPDGDGTRC
     DLGVTLTQRE LASLAGLALN TAEKSLAALT AKGLVERSYR TITICDVPKL LEFAKVVADN
     PY
//