ID A0A0M2GS18_9ACTN Unreviewed; 742 AA.
AC A0A0M2GS18;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KJK38200.1};
GN ORFNames=UK15_18235 {ECO:0000313|EMBL:KJK38200.1};
OS Streptomyces variegatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK38200.1, ECO:0000313|Proteomes:UP000034786};
RN [1] {ECO:0000313|Proteomes:UP000034786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK38200.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYJH01000012; KJK38200.1; -; Genomic_DNA.
DR RefSeq; WP_031136786.1; NZ_JYJH01000012.1.
DR AlphaFoldDB; A0A0M2GS18; -.
DR STRING; 284040.UK15_18235; -.
DR PATRIC; fig|284040.3.peg.1458; -.
DR Proteomes; UP000034786; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR36511:SF3; ANTITOXIN HIGA-2; 1.
DR PANTHER; PTHR36511; MERR FAMILY BACTERIAL REGULATORY PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 25..77
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 84..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..113
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 79975 MW; 2080FAE629AC88E3 CRC64;
MSELFDAVDA LIASRSPLPP PAERKRLRQA HGLTLDEVAA ALQVRRATVS GWEAGKTEPR
PPERDAYARL LKQLAQLYPA SAPVPPEETV VPETPAVPAA PVPSVPEPAE TRTAPPGPAT
EDAPGNTARR PVGPGAVPRP AATSGPTSRR PAARKAAPAG TSANNTDSRF DNGPLAVVDV
DADGQVLAYC VGGLVLDVPA KSLPALVEWT LDQGRLGQPK LSGPGKDADP LVVLTGAACE
RYGLPVTLTG QERLAGRLPE SHKVIKQLTR ADWQLTKRGL GPWARIYRPA QGAERSCVQL
CIPSWDALDT RHWANAGQLP PADLARLLGT YAARVMTPRG STAVTGLELM TALHPPTRAS
EPDADGRRHS EHNPGSLGRN PVDCAPCEAP DGHPLLANLP RFHHRTPAEV LVEEAYDWAR
PLTDAECLRR HLVGIDVNMA FAAGANGLTV GLGAPNHVKN PVFDAKLPGS WLVDLSHVDL
ARVKLAKEWT DLDGDLLPSP FTPKGERPTG PAWYATPTVA YAVELGYEVR PIEAYVRHDN
GRYLDAWYNR LRDAYLATMA DLGVSADLPP REFLAAMEGY RQRDPQLAIV VSAIKATVKG
GIGKLRERPR GEGWKPGQSW RALARPTWRP DIRAAVISRT RVNMHRKIVK HAAFTGQYPV
AVLSDCAVYA SDGPSPLDFL PYRDDKPLPG GFKLGVNPGL VKHEGTQSVL WGEGVREQFN
APELNLARYI KDGTVTDQDT GE
//
