ID A0A0M2GUA0_9ACTN Unreviewed; 395 AA.
AC A0A0M2GUA0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:KJK39738.1};
GN ORFNames=UK15_10805 {ECO:0000313|EMBL:KJK39738.1};
OS Streptomyces variegatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK39738.1, ECO:0000313|Proteomes:UP000034786};
RN [1] {ECO:0000313|Proteomes:UP000034786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK39738.1}.
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DR EMBL; JYJH01000006; KJK39738.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2GUA0; -.
DR STRING; 284040.UK15_10805; -.
DR PATRIC; fig|284040.3.peg.6582; -.
DR Proteomes; UP000034786; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:KJK39738.1};
KW Hydrolase {ECO:0000313|EMBL:KJK39738.1};
KW Nuclease {ECO:0000313|EMBL:KJK39738.1}.
FT DOMAIN 214..294
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 395 AA; 42604 MW; 0FA3C492D7C3E6D8 CRC64;
MLEPREGIPP VIADETALAR VIAAFEAGSG PVAVDAERAS GYRYGQRAYL VQLRREGAGT
ALVDPVACPD LSALGDALSG VEWVLHAATQ DLPCLREIGM VPTRLFDTEL AGRLAGFPRV
GLGAMVESVL GFVLEKGHSA VDWSTRPLPE PWLRYAALDV ELLVDLRDAL EKELDRQGKL
EWARQEFDAI ASAPPPEPRK DPWRRTSGMH KVRRRRQLAV VRELWQTRDR IAQRRDVSPG
KVLGDAAIVE AALALPANVH ALAALNGFGH RAGKRQLEQW QAAVDRAKGL SEAQLPQPGQ
AVTGPPPPRA WADKDPAAAA RLSAARAGIS ALAEQLGMPQ ENLITPDTVR RVCWEPPAVV
DTESVAAALA GHGARPWQVE QVTPVLVEAL SAKEA
//
