ID A0A0M2HJW2_9MICO Unreviewed; 347 AA.
AC A0A0M2HJW2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Lactose operon repressor {ECO:0000313|EMBL:KJL47045.1};
GN Name=lacI_9 {ECO:0000313|EMBL:KJL47045.1};
GN ORFNames=RS84_03692 {ECO:0000313|EMBL:KJL47045.1};
OS Microbacterium hydrocarbonoxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=273678 {ECO:0000313|EMBL:KJL47045.1, ECO:0000313|Proteomes:UP000033900};
RN [1] {ECO:0000313|EMBL:KJL47045.1, ECO:0000313|Proteomes:UP000033900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA35 {ECO:0000313|EMBL:KJL47045.1,
RC ECO:0000313|Proteomes:UP000033900};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL47045.1}.
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DR EMBL; JYJB01000010; KJL47045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2HJW2; -.
DR STRING; 273678.RS84_03692; -.
DR PATRIC; fig|273678.4.peg.3686; -.
DR Proteomes; UP000033900; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033900};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..72
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 37177 MW; 8EF433AB9826D12A CRC64;
MIVSEHGTAE SPQRRREPSM EDVAREAGVS GQTVSRVVNA RGYVGAATRE RVEAAMQRLG
YRPNSAARAL RSGRFRTIGV VMFSFSSYGN QRTLDAIAVR AAELGYALTL IPVASSARET
VAGAFRRLEE HAVDGIIIVI EAHQLDEADI EIPDALPVVF VDSNRSAEHP FVDTDQAQGA
RLATEHLLDL GHHTVWHVAG PAKSYSAERR REAWQSTLES RGLEVPEAIE GDWSAASGHE
AGRRLASTGG VTAVFAANDQ MAIGVLRAFR EAGLDVPGDI SVVGFDGLPD AAQLWPPLTT
VQQHPERVGA LAVDALLAEL EGEERVQTPL VGTELVVRAS TAAPRSS
//
