ID A0A0M2HPJ5_9MICO Unreviewed; 784 AA.
AC A0A0M2HPJ5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA_3 {ECO:0000313|EMBL:KJL46391.1};
GN ORFNames=RS84_03023 {ECO:0000313|EMBL:KJL46391.1};
OS Microbacterium hydrocarbonoxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=273678 {ECO:0000313|EMBL:KJL46391.1, ECO:0000313|Proteomes:UP000033900};
RN [1] {ECO:0000313|EMBL:KJL46391.1, ECO:0000313|Proteomes:UP000033900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA35 {ECO:0000313|EMBL:KJL46391.1,
RC ECO:0000313|Proteomes:UP000033900};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL46391.1}.
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DR EMBL; JYJB01000010; KJL46391.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2HPJ5; -.
DR STRING; 273678.RS84_03023; -.
DR PATRIC; fig|273678.4.peg.3022; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000033900; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152:SF2; DRUG RESISTANCE ABC TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000033900};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 472..773
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 784 AA; 82946 MW; 17E2C079B17DFF3D CRC64;
MTVEHPADTH DIIRVQGARE NNLKEVSVDI PKRRLTVFTG VSGSGKSSLV FDTIAAESRR
MIDETYSAFV QGFMPSVPRP DVDVLEGLTT AIIVDQERLG ANPRSTVGTV TDANAMLRIL
FSKLGQPYIG GPTAFSFNIP TQKASGVMTG PGGEKKIVKD AIYLGGMCPR CEGRGAVSDL
DLAQIVDESK SLNEGAIMVP GYTADGWMVK GFSESGFYPA DKPIASFTEK QRHLFLYGEV
TKVKISGINM TYEGLIPKIT KSMLSKDLDA LQPHIRAFVE RVATFATCPE CDGTRLTEGA
RSSKIDGISI ADACRMQVTD LADWVRGLTL PGAGPLLDAL SANLDAFVTL GLGYLSLERP
SGTLSGGEAQ RIKMLRHLGS SLTDVTYVFD EPTIGLHPHD IQRMNSLLLR LRDKGNTVLV
VEHKPETIVI ADHVVDLGPG AGSAGGEICF EGTVEGLKGS GTKTGTHLDD RAALKESVRS
GAGSIEVRGA NANNLQNVDV DIPKGVLTVV TGVAGSGKSS LIHGSVSKRE GVVAIDQGAI
KGSRRSNPAT YTGLLEPIRK AFAKANGVKP ALFSANSEGA CPTCKGAGVI ITELGFMDTI
ETPCEDCGGK RFQAAVLEYK LAGKDITEVL DLPVAEARVF FSEGEAKLPA AAAILGRLED
VGLGYLSLGQ PLSTLSGGER QRIKLAIQMG EKGDVYVLDE PTTGLHLADV QNILGLLDRL
VESGKTVIVI EHHQAVMAHA DWLIDIGPGA GHDGGRVVFE GTPAELVAAK STLTGEHLAE
YVGA
//
