ID A0A0M2HQB0_9MICO Unreviewed; 416 AA.
AC A0A0M2HQB0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN Name=dhbC {ECO:0000313|EMBL:KJL48942.1};
GN ORFNames=RS84_00572 {ECO:0000313|EMBL:KJL48942.1};
OS Microbacterium hydrocarbonoxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=273678 {ECO:0000313|EMBL:KJL48942.1, ECO:0000313|Proteomes:UP000033900};
RN [1] {ECO:0000313|EMBL:KJL48942.1, ECO:0000313|Proteomes:UP000033900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA35 {ECO:0000313|EMBL:KJL48942.1,
RC ECO:0000313|Proteomes:UP000033900};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL48942.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYJB01000005; KJL48942.1; -; Genomic_DNA.
DR RefSeq; WP_045256245.1; NZ_JYJB01000005.1.
DR AlphaFoldDB; A0A0M2HQB0; -.
DR STRING; 273678.RS84_00572; -.
DR PATRIC; fig|273678.4.peg.564; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000033900; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:KJL48942.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033900}.
FT DOMAIN 155..407
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 416 AA; 43143 MW; 3C863728E39F3EF7 CRC64;
MSTKLVVETR EIDPVEDLLA YADPDQPLAW LRRGDGIVAA GDRIVTAIRV PAGTDAARSA
IIASAWRQLA QDADIDDPLG LPGTGLVGFG ALAFDEHSIA DSVLLVPSAV IGRHRGRSWL
TRIRTADSAP STAPAAKTYG PHWAGTVGPG AQSPQGYQDS VRGALARIAD GELSKVVLAR
DLTGSIPAGS DLRRLVRALS TGYPDTWAFA VDGLIGASPE TLVTVQNRTV TARVLAGTIG
RGADADADTA ASAHLASSTK DLDEHEYAVQ SVLASLRPHT RVLAASEQPF LLKLPNLFHL
ATDVEGELAE GESSLDLVGA LHPTAAVAGT PTVAAIAAIR QLEPFDRGRY AGPVGWVDAA
GNGEWAIALR CAQFTGGAGE IAVTAYAGAG IVAGSDPESE LLETRVKFRP LVDALA
//
