ID A0A0M2HRY6_9MICO Unreviewed; 547 AA.
AC A0A0M2HRY6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=RS84_00173 {ECO:0000313|EMBL:KJL49461.1};
OS Microbacterium hydrocarbonoxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=273678 {ECO:0000313|EMBL:KJL49461.1, ECO:0000313|Proteomes:UP000033900};
RN [1] {ECO:0000313|EMBL:KJL49461.1, ECO:0000313|Proteomes:UP000033900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA35 {ECO:0000313|EMBL:KJL49461.1,
RC ECO:0000313|Proteomes:UP000033900};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL49461.1}.
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DR EMBL; JYJB01000003; KJL49461.1; -; Genomic_DNA.
DR RefSeq; WP_045255861.1; NZ_JYJB01000003.1.
DR AlphaFoldDB; A0A0M2HRY6; -.
DR STRING; 273678.RS84_00173; -.
DR PATRIC; fig|273678.4.peg.164; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000033900; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000033900}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 399..544
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 60500 MW; 0784D889F2765DC5 CRC64;
MSDGPLIVQS DRTVLLEVAH ADAEAARHEL AIFAELERAP EHIHTYRITR LGLWNARAAG
HTAEDMLETL DRWSRFPVPP SVSVDLRETV NRYGRLVIER DGEGTLILRS NDPAVLTQVA
NNKRIQPLLI GHPTPDTFVV DAWARGQIKQ ELLKIGWPAE DLAGYTPGTP HDIELAEDGW
QIRPYQQDAV DAFSKDGSGV VVLPCGAGKT IVGAGAMAAT KTTTLILVTN TVSARQWRDE
LLKRTSLTPE EIGEYSGQAK EVKPVTIATY QILTAKRKGE YAHLALLDAL DWGLIVYDEV
HLLPAPVFKL TADLQARRRI GLTATLVRED GREGDVFSLI GPKRFDAPWK QIEAQGFISP
AVCYEVRVDL PPSDRLEYAA ATDDERYRLA ASAPAKIDAV KELIAKHPDE QILVIGQYLD
QLDTLADALD APQITGATPV DEREELYRQF REGEIQLLVV SKVANFSIDL PEASVAIQVS
GSFGSRQEEA QRLGRLLRPK QSGHTASFYT LVARDTIDQD YAQNRQRFLA EQGYSYTIMD
ADALDAA
//
