ID A0A0M2HS20_9MICO Unreviewed; 332 AA.
AC A0A0M2HS20;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Lactose operon repressor {ECO:0000313|EMBL:KJL47268.1};
GN Name=lacI_7 {ECO:0000313|EMBL:KJL47268.1};
GN ORFNames=RS84_02058 {ECO:0000313|EMBL:KJL47268.1};
OS Microbacterium hydrocarbonoxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=273678 {ECO:0000313|EMBL:KJL47268.1, ECO:0000313|Proteomes:UP000033900};
RN [1] {ECO:0000313|EMBL:KJL47268.1, ECO:0000313|Proteomes:UP000033900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA35 {ECO:0000313|EMBL:KJL47268.1,
RC ECO:0000313|Proteomes:UP000033900};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL47268.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYJB01000009; KJL47268.1; -; Genomic_DNA.
DR RefSeq; WP_045257683.1; NZ_JYJB01000009.1.
DR AlphaFoldDB; A0A0M2HS20; -.
DR STRING; 273678.RS84_02058; -.
DR PATRIC; fig|273678.4.peg.2061; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000033900; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033900};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 332 AA; 35524 MW; 6615F5DC3B3401BD CRC64;
MQKRTTSRDV ARLAGVSQAT VSYVFTGKDT ISAPTRDRVL RAAAELNYQP NLAARSMRTS
RTGRLAVVMT VSSLNPRELL LGATEAASEA GYVIEVVYLP GGPDERAARL AQLVSSSQYE
GILSFSPIPV SPASADAEPG ATVVLSLSEF DDDMHVTGEF TDARPIAEMM ERLVQLGHRR
FVHITGALDF PSAISRRDEY LAAVERLGVE SLGVIEGDWS AETGYRIAQA LPDTAPPFAL
IAANDLVATG AMRAAIQRGW HIPSDMSVTG WDDAGQSAYL VPSLTTVVQD RQTLGANAAR
RLIAAVRREP VPAPATGLQH IVWRESTAAP SS
//
