ID A0A0M2JPF5_9MYCO Unreviewed; 844 AA.
AC A0A0M2JPF5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Protein translocase subunit SecA {ECO:0000256|RuleBase:RU003874};
DE Flags: Fragment;
GN ORFNames=WN67_29595 {ECO:0000313|EMBL:KKE98376.1};
OS Mycolicibacterium obuense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1807 {ECO:0000313|EMBL:KKE98376.1, ECO:0000313|Proteomes:UP000034150};
RN [1] {ECO:0000313|EMBL:KKE98376.1, ECO:0000313|Proteomes:UP000034150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UC1 {ECO:0000313|EMBL:KKE98376.1,
RC ECO:0000313|Proteomes:UP000034150};
RA Greninger A.L., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium obuense UC1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SecA family. {ECO:0000256|ARBA:ARBA00007650,
CC ECO:0000256|RuleBase:RU003874}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKE98376.1}.
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DR EMBL; LAUZ02000175; KKE98376.1; -; Genomic_DNA.
DR RefSeq; WP_046366666.1; NZ_LAUZ02000175.1.
DR AlphaFoldDB; A0A0M2JPF5; -.
DR STRING; 1807.MOBUDSM44075_00872; -.
DR OrthoDB; 9805579at2; -.
DR Proteomes; UP000034150; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR CDD; cd17928; DEXDc_SecA; 1.
DR CDD; cd18803; SF2_C_secA; 1.
DR Gene3D; 1.10.3060.10; Helical scaffold and wing domains of SecA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.90.1440.10; SecA, preprotein cross-linking domain; 1.
DR HAMAP; MF_01382; SecA; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000185; SecA.
DR InterPro; IPR020937; SecA_CS.
DR InterPro; IPR011115; SecA_DEAD.
DR InterPro; IPR014018; SecA_motor_DEAD.
DR InterPro; IPR011130; SecA_preprotein_X-link_dom.
DR InterPro; IPR044722; SecA_SF2_C.
DR InterPro; IPR011116; SecA_Wing/Scaffold.
DR InterPro; IPR036266; SecA_Wing/Scaffold_sf.
DR InterPro; IPR036670; SecA_X-link_sf.
DR NCBIfam; TIGR00963; secA; 1.
DR PANTHER; PTHR30612:SF0; CHLOROPLAST PROTEIN-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR30612; SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; 1.
DR Pfam; PF21090; P-loop_SecA; 1.
DR Pfam; PF07517; SecA_DEAD; 1.
DR Pfam; PF01043; SecA_PP_bind; 1.
DR Pfam; PF07516; SecA_SW; 1.
DR PRINTS; PR00906; SECA.
DR SMART; SM00957; SecA_DEAD; 1.
DR SMART; SM00958; SecA_PP_bind; 1.
DR SUPFAM; SSF81886; Helical scaffold and wing domains of SecA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF81767; Pre-protein crosslinking domain of SecA; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS01312; SECA; 1.
DR PROSITE; PS51196; SECA_MOTOR_DEAD; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003874};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003874};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU003874};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|RuleBase:RU003874};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003874}.
FT DOMAIN 1..612
FT /note="SecA family profile"
FT /evidence="ECO:0000259|PROSITE:PS51196"
FT DOMAIN 85..242
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 416..617
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT COILED 730..757
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 844
FT /evidence="ECO:0000313|EMBL:KKE98376.1"
SQ SEQUENCE 844 AA; 94706 MW; 6F16D81774633836 CRC64;
MLSKLLRLGE GRMVKRLKGV ADYVNTLSDD VEKLSDAELR AKTAAFKARL ADGEDLDDLL
PEAFAVAREA AWRVLNQRHF DVQVMGGAAL HFGNVAEMKT GEGKTLTAVL PAYLNALTGK
GVHIVTVNDY LAKRDAEQMG RVHRFLGLDV GVILSQLTPD ERRTAYAADI TYGTNVEFGF
DYLRDNMALR LEDCVQRGFN YAIVDEVDSI LIDEARTPLI ISGPVDGSSN WYSEFARLAP
LMEKDTHYEV DLKKRTVGVH EAGVAFVEDQ LGIENLYEAA NSPLVSYLNN ALKAKELFER
DKHYIVRNGE VLIVDEFTGR MLVGRRYNEG LHQAIEAKEQ VEIKAENQTV ATVTLQNYFR
MYDKLAGMTG TAETEAAELH EIYKLGVVPI PTNKPMIRAD QSDLIYKTEE AKFIAVVDDV
TERYEKGQPV LIGTTSVERS EFLARQFEKR RIPHNVLNAK YHEQEAGIIA EAGRVGAVTV
ATNMAGRGTD IVLGGNVDYL LDRQLRQRGL DPIETPDEYE AAWHEELPAV KAQVSSEAKD
VVAAGGLYVL GTERHESRRI DNQLRGRSGR QGDPGESRFY LSLADELMRR FNGATLETLL
TRLNLPDDVP IEAKMVSRAI KSAQTQVEQQ NFDIRKEVLK YDEVMNQQRK VIYAERRRIL
EGENLAEQAH TMLVDVITAY VDGATAEGYS EDWDLEKLWE SLRQLYPVGI DHNDLIDSDA
VGEPGELTRK ELLDALLEDA ERAYAAREAE IESLAGEGAM RQLERNVLLN VLDRKWREHL
YEMDYLREGI GLRGLAQQRP EVEYAREGFD MFIGMLDGMK EESVGFLFNV QVEAAPQPAV
APVA
//
