ID A0A0M2KH28_9GAMM Unreviewed; 342 AA.
AC A0A0M2KH28;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ECA polysaccharide chain length modulation protein {ECO:0000256|HAMAP-Rule:MF_02025};
GN Name=wzzE {ECO:0000256|HAMAP-Rule:MF_02025};
GN ORFNames=SY86_15605 {ECO:0000313|EMBL:KKF36538.1};
OS Erwinia tracheiphila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=65700 {ECO:0000313|EMBL:KKF36538.1, ECO:0000313|Proteomes:UP000033924};
RN [1] {ECO:0000313|EMBL:KKF36538.1, ECO:0000313|Proteomes:UP000033924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BuffGH {ECO:0000313|EMBL:KKF36538.1,
RC ECO:0000313|Proteomes:UP000033924};
RA Shapiro L.R.;
RT "Erwinia tracheiphila.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Modulates the polysaccharide chain length of enterobacterial
CC common antigen (ECA). {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and WzzE.
CC {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_02025}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_02025}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the WzzB/Cld/Rol family. {ECO:0000256|HAMAP-
CC Rule:MF_02025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF36538.1}.
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DR EMBL; JXNU01000003; KKF36538.1; -; Genomic_DNA.
DR RefSeq; WP_016192344.1; NZ_JXNU01000003.1.
DR AlphaFoldDB; A0A0M2KH28; -.
DR STRING; 65700.SY86_15605; -.
DR PATRIC; fig|65700.7.peg.3904; -.
DR UniPathway; UPA00566; -.
DR Proteomes; UP000033924; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1890.10; FepE-like; 1.
DR HAMAP; MF_02025; WzzE; 1.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR032895; WzzE.
DR PANTHER; PTHR32309:SF16; ECA POLYSACCHARIDE CHAIN LENGTH MODULATION PROTEIN; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF160355; Bacterial polysaccharide co-polymerase-like; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02025};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_02025};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_02025};
KW Reference proteome {ECO:0000313|Proteomes:UP000033924};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_02025};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_02025}.
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02025"
FT TRANSMEM 317..337
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02025"
FT DOMAIN 9..83
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
SQ SEQUENCE 342 AA; 38561 MW; 174482D118EF5F95 CRC64;
MMHPDVADNE LDIRGLCCAL WHGKRWIIGV ALIFALLAYI WSLLVTPQWS TTAITDRPTV
NMMSGFYSQQ QFLNNLDSRN NNNTFIAPSV SDGVYREFVM QLSSYDTRRD FWLQSDYYKK
HQTGNASKDA MLLDELIADI QFQPADSAKN LNDTVRLVAE TAPDANNLLR QYVVFANQRA
AAHLNEELAG AWSARTVQLK AQVKRQEAVA KAIYGRQVNS VQQALKILQQ QGLEQAKSNM
PSEQLPDSEL FLLGRAVLQA RLENLQASGP DYDIDYDQNK AMLNTLNVGP TLVNTFKTWR
YLRTPEEPAK RDSPRCVFLM VMWGAVGALT GAGTALVRRR RA
//
