ID A0A0M2LFH1_9MICO Unreviewed; 396 AA.
AC A0A0M2LFH1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=tRNA-dihydrouridine synthase {ECO:0000313|EMBL:KKI16556.1};
GN ORFNames=XM48_15455 {ECO:0000313|EMBL:KKI16556.1};
OS Leucobacter sp. Ag1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=1642040 {ECO:0000313|EMBL:KKI16556.1, ECO:0000313|Proteomes:UP000033836};
RN [1] {ECO:0000313|EMBL:KKI16556.1, ECO:0000313|Proteomes:UP000033836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ag1 {ECO:0000313|EMBL:KKI16556.1,
RC ECO:0000313|Proteomes:UP000033836};
RA Pei D., Kukutla P., Yu W., Xu J.;
RT "Draft Genome Sequences of Leucobacter sp. Ag1 from Mosquito Anopheles
RT gambiae.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKI16556.1}.
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DR EMBL; LAYO01000110; KKI16556.1; -; Genomic_DNA.
DR RefSeq; WP_046456723.1; NZ_LAYO01000110.1.
DR AlphaFoldDB; A0A0M2LFH1; -.
DR STRING; 1642040.XM48_15455; -.
DR PATRIC; fig|1642040.3.peg.1742; -.
DR OrthoDB; 9764501at2; -.
DR Proteomes; UP000033836; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
DR CDD; cd02801; DUS_like_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR035587; DUS-like_FMN-bd.
DR InterPro; IPR004652; DusB-like.
DR InterPro; IPR024036; tRNA-dHydroUridine_Synthase_C.
DR InterPro; IPR018517; tRNA_hU_synthase_CS.
DR NCBIfam; TIGR00737; nifR3_yhdG; 1.
DR PANTHER; PTHR45846; TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE; 1.
DR PANTHER; PTHR45846:SF1; TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE; 1.
DR Pfam; PF01207; Dus; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS01136; UPF0034; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000033836};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 25..335
FT /note="DUS-like FMN-binding"
FT /evidence="ECO:0000259|Pfam:PF01207"
FT REGION 347..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 42947 MW; 93564153AC420347 CRC64;
MTSSSLATDQ RLRIGPIALD VPVVLAPMAG ITNTAFRRLC REYGAGLYVS EMITSRALVE
RTPASMRLIK HHESETPRSI QLYGVDPKTV SEAVKFLVAE DRADHIDLNF GCPVPKVTRK
GGGSALPWKQ DLFKAIVEGA VKAAGDIPLT VKMRKGIDAD HLTFLDAART AEDAGVAAIA
LHGRTANEFY SGHADWSAIA ELKQTITSVP VLGNGDIWSA EDAIRMVRET GCDGVVVGRG
CLGRPWLFGD LAAAFRAEQG EISREAAEAA IAKPPLGFVM QAMRRHTELL VEFFDGEEDR
ACRDIRKHVA WYFKGYGVGG DTRRSLAAVE SLEQMDEIFA TMDGSMPYPG EGAEGQRGRA
GSPKRVVLPD RWLESRTSDG IDFAELAEAE RDDSGG
//
