ID A0A0M2LLJ6_9MICO Unreviewed; 498 AA.
AC A0A0M2LLJ6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Betaine-aldehyde dehydrogenase {ECO:0000313|EMBL:KKI16629.1};
DE EC=1.2.1.8 {ECO:0000313|EMBL:KKI16629.1};
GN ORFNames=XM48_14450 {ECO:0000313|EMBL:KKI16629.1};
OS Leucobacter sp. Ag1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=1642040 {ECO:0000313|EMBL:KKI16629.1, ECO:0000313|Proteomes:UP000033836};
RN [1] {ECO:0000313|EMBL:KKI16629.1, ECO:0000313|Proteomes:UP000033836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ag1 {ECO:0000313|EMBL:KKI16629.1,
RC ECO:0000313|Proteomes:UP000033836};
RA Pei D., Kukutla P., Yu W., Xu J.;
RT "Draft Genome Sequences of Leucobacter sp. Ag1 from Mosquito Anopheles
RT gambiae.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKI16629.1}.
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DR EMBL; LAYO01000109; KKI16629.1; -; Genomic_DNA.
DR RefSeq; WP_046456543.1; NZ_LAYO01000109.1.
DR AlphaFoldDB; A0A0M2LLJ6; -.
DR STRING; 1642040.XM48_14450; -.
DR PATRIC; fig|1642040.3.peg.628; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000033836; Unassembled WGS sequence.
DR GO; GO:0018480; F:5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity; IEA:InterPro.
DR GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:1901023; P:4-hydroxyphenylacetate catabolic process; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR011985; DH_HpaE.
DR NCBIfam; TIGR02299; HpaE; 1.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000033836}.
FT DOMAIN 21..481
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 258
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 498 AA; 53789 MW; FFCEA731A8EF1B6D CRC64;
MTHQKPEGLP EKIQLFIDGE FVDAQDGATF DVIEPVSNEV YITAASAGKA DVDRAVAAAK
RAFDEGPWPK MLPRERSRIL HRVADIVESR DEQLALLESW DSGLPITQAK GQARRAAENF
RFFADLIVAE HDNVTKVPGR QINYVNRKPK GVAGLITPWN VPFMQESWKL APAIATGNTV
VLKPASYTPL SAALWPEIFR EAGVPEGVFN LILGSGGVAG DALVKHPDVP LISFTGDSST
GAMISTNAAP FLKGLSLELG GKSPSVVFAD ADLEEALDAT VFSVFSLNGE RCTAGSRVLV
ERSIYDDFVA RYSERAKNIV IGLPSDPATE VGALVHPSHF EKVMSYVEIG KSEGRLVAGG
GRPEGFPEGN YVAPTVFADV KPDARIFQEE IFGPVVAITP FDTDEEALEL ANDTKYGLAA
YVWTSNLKRA HNFAHGIESG MVWLNSNNVR DLRTPFGGVK ASGLGREGGY RSVDFYTTAQ
SIQITLNEAH SPRFGAGK
//
