ID A0A0M2RBD7_9PROT Unreviewed; 881 AA.
AC A0A0M2RBD7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982, ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN ORFNames=WH95_08780 {ECO:0000313|EMBL:KKJ77310.1};
OS Kiloniella litopenaei.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Kiloniellaceae; Kiloniella.
OX NCBI_TaxID=1549748 {ECO:0000313|EMBL:KKJ77310.1, ECO:0000313|Proteomes:UP000034491};
RN [1] {ECO:0000313|EMBL:KKJ77310.1, ECO:0000313|Proteomes:UP000034491}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1-1 {ECO:0000313|EMBL:KKJ77310.1,
RC ECO:0000313|Proteomes:UP000034491};
RA Shao Z., Wang L., Li X.;
RT "Genome sequence of Kiloniella sp. P1-1, isolated from the gut microflora
RT of Pacific white shrimp, Penaeus vannamei.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647,
CC ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKJ77310.1}.
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DR EMBL; LANI01000005; KKJ77310.1; -; Genomic_DNA.
DR RefSeq; WP_046506152.1; NZ_LANI01000005.1.
DR AlphaFoldDB; A0A0M2RBD7; -.
DR STRING; 1549748.WH95_08780; -.
DR PATRIC; fig|1549748.8.peg.3773; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000034491; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000034491}.
FT DOMAIN 705..721
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 631..638
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 881 AA; 96458 MW; 9B860114C4DF82B4 CRC64;
MMAQYLEIKA DHPDSLLFYR MGDFYELFFE DAVQASEALD ITLTKRGHHK GDDIPMCGVP
FHAAEGYLSR LIRKGFKVAI CEQMENPAEA KKRGAKSVVK RGVVRLVTPG TITEDELLDA
RSHNYLAALT DAAGDYGLSW LDMSTGDFYT QPLEASEKNI NGVLLAALAR LNPGELLLPE
RLFLREELAD VVNEWRSILS PLPSSRFDSE NARRRLEDVF SIKALDAFGE FSRAEVAASG
SLLDYVELTQ KGKLPRLSSP KRVRSDAVME IDAATRRNLE LTQALTGGRK GSLLATIDRT
VTGAGARLLG SRIAAPLTEP EAISHRLNMV SWFVEEDGLR QDLRASLRQC PDIERGLSRL
TVGRGGPRDV AGIRDALHEA GRLKSILSGV QPDSLPEGIK NCIKNLGDHR ELCDVLQRAL
LDDLPLLARD GGFIAAGFSP ELDEYKQLRD DSRKLIAGLQ ARYAKITGVN SLKVKHNNVL
GYFIEVSSTN ASKVNIDAES EFIHRQTLAS AMRFTTVELS DLEQKISGAA GKALAIELEL
YDDLIAKVIE QADQIALAAR TLAELDVNAA LAELAVSERW NRPKVDGSLA FDIVAGRHPV
VEAALSRTSE GPFVANNCTL EDQQRLWLIT GPNMAGKSTF LRQNALIAVL AQMGSFVPAE
SAHIGSVDRL FSRVGAADDL ARGRSTFMVE MVETAVILNQ STERSLVILD EIGRGTATYD
GLSIAWACVE HLHETNKSRA LFATHYHELT SLTSKLKSLS CHSMRVKEWK GEVVFLHEVT
NGAADRSYGI HVAKLAGLPV AAVTRAEQVL ETLEKDGQAG NLTHLAEDLP LFASLPTTTA
EADVEKGVSV VDQRLSEINV DDLTPRQALD LLYELKAVDQ E
//
