ID A0A0M2RK90_9ACTN Unreviewed; 403 AA.
AC A0A0M2RK90;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Acid phosphatase {ECO:0000313|EMBL:KKJ95316.1};
GN ORFNames=LQ51_26875 {ECO:0000313|EMBL:KKJ95316.1};
OS Micromonospora sp. HK10.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1538294 {ECO:0000313|EMBL:KKJ95316.1, ECO:0000313|Proteomes:UP000034330};
RN [1] {ECO:0000313|EMBL:KKJ95316.1, ECO:0000313|Proteomes:UP000034330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK10 {ECO:0000313|EMBL:KKJ95316.1,
RC ECO:0000313|Proteomes:UP000034330};
RA Talukdar M., Das D., Borah C., Deka Boruah H.P., Bora T.C., Singh A.K.;
RT "Draft genome sequence of Micromonospora HK10, isolated from Kaziranga
RT National park, Assam, India.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKJ95316.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JTGL01000212; KKJ95316.1; -; Genomic_DNA.
DR RefSeq; WP_046563197.1; NZ_KQ058682.1.
DR AlphaFoldDB; A0A0M2RK90; -.
DR STRING; 1538294.LQ51_26875; -.
DR PATRIC; fig|1538294.3.peg.746; -.
DR HOGENOM; CLU_035712_0_0_11; -.
DR OrthoDB; 5296884at2; -.
DR Proteomes; UP000034330; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR014636; RNaseH/PGlycerate_mutase.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF1; PHOSPHOGLYCERATE MUTASE PMU1-RELATED; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR PIRSF; PIRSF036922; RNaseH_PGAM; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
FT DOMAIN 2..142
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 138..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 206
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 282
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 257
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 403 AA; 42252 MW; 5AA7207D8A271768 CRC64;
MAVRAVVVEA DGGSRGNPGP AGYGAVVRDP ETGEVLAERS AAIGTSTNNV AEYRGLIAGL
EAAAELGAAE VEARLDSKLV VEQMCGRWQI RHPGLRPLAA QAAGLVGRFE RVRFSWVPRE
RNTHADALAN AAMDAAAGAP PAAVSPRTAE PPREVAGPDS PARAAAREVA ARAAVGRATG
TDPATTPASW EPRPTEEGTR LILVRHGETE RTVQKRYSGR GDVALTDRGR AQARATAARV
AALAPSVAAV VSSPLSRCTA TAEAIAALVG DPPVRVDDDL IECDFGVWEG RTFAEVRADW
AGELDAWLAS TRVAPPEGES FAAVAERTGR AVDRLRRAYP GETVVVVSHV SPIKLVLRDA
LAADDSFLHR LYLDTAGISV LDLYPDGGVA VRSVNDTAHL NDI
//
