ID A0A0M2RTI8_9ACTN Unreviewed; 706 AA.
AC A0A0M2RTI8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KKJ98567.1};
GN ORFNames=LQ51_24400 {ECO:0000313|EMBL:KKJ98567.1};
OS Micromonospora sp. HK10.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1538294 {ECO:0000313|EMBL:KKJ98567.1, ECO:0000313|Proteomes:UP000034330};
RN [1] {ECO:0000313|EMBL:KKJ98567.1, ECO:0000313|Proteomes:UP000034330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK10 {ECO:0000313|EMBL:KKJ98567.1,
RC ECO:0000313|Proteomes:UP000034330};
RA Talukdar M., Das D., Borah C., Deka Boruah H.P., Bora T.C., Singh A.K.;
RT "Draft genome sequence of Micromonospora HK10, isolated from Kaziranga
RT National park, Assam, India.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKJ98567.1}.
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DR EMBL; JTGL01000185; KKJ98567.1; -; Genomic_DNA.
DR RefSeq; WP_046571875.1; NZ_KQ058902.1.
DR AlphaFoldDB; A0A0M2RTI8; -.
DR STRING; 1538294.LQ51_24400; -.
DR PATRIC; fig|1538294.3.peg.6494; -.
DR HOGENOM; CLU_005108_4_1_11; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000034330; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 173..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 233..328
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 552..680
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 706 AA; 74237 MW; B38A16ECDE0E6A34 CRC64;
MAGGRSRWTA TLVAVALVLA WLVVGGIAGP YAGKLGDVAT NDNAAFLPTD AEATRAQDLA
AGFVEKETTP ALVVYERPTG ITPADQQRIQ ADAARFGQLP GVVAPLPPPI PSQDRQAVQV
VVPIDAAEGE QIGAVVDRLR EIAGPDRDGL TVDVAGPAGL LADLIEVFTA IDGPLLLVTL
VVVLVILLIV YRSPVLWVFP LLAAGMSYSL AAVFVYVLAR DDVIKLNGQA QGILTVLVFG
AGTDYALLLI ARYREELHRH ERPWDALWAA WKGAAPAIVA SGATVIVSLL CLLLSSLNSN
RALGPVAAVG IAATLLVMLT FLPALLLLGG RWAFWPRRPR HDDADPQAEH GIWGRVAGFV
ARRARVIWLV TAVALAALAL GVTQLNATAL GQSDLFTKRT DSVAGQEVIA RHYPAGTGSP
ATIFANQATA EQVARAAQGV PGVASVRPFT RQAGPPAADA PPTVVDGRVQ LEATLADPPD
SDRAERTLRA LRETLHRVPG ADAVVGGFTA INVDTADAST RDRNVIIPVV LLVIAVILAV
LLRALVAPLL LIATVVLSFL ATLGLCALVF RYVLDFPGVD QSFPLFAFVF LVALGIDYNI
FLMSRVREES VRRGTRAGVL AGLAVTGGVI TSAGIVLAAT FSALAVLPLV VLVELGVAVA
VGVLLDTIVV RSLLVPALSY DIGARIWWPS RLSRTHRAGA EVTRGR
//
