ID A0A0M2RU01_9ACTN Unreviewed; 750 AA.
AC A0A0M2RU01;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=LQ51_19580 {ECO:0000313|EMBL:KKK03535.1};
OS Micromonospora sp. HK10.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1538294 {ECO:0000313|EMBL:KKK03535.1, ECO:0000313|Proteomes:UP000034330};
RN [1] {ECO:0000313|EMBL:KKK03535.1, ECO:0000313|Proteomes:UP000034330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK10 {ECO:0000313|EMBL:KKK03535.1,
RC ECO:0000313|Proteomes:UP000034330};
RA Talukdar M., Das D., Borah C., Deka Boruah H.P., Bora T.C., Singh A.K.;
RT "Draft genome sequence of Micromonospora HK10, isolated from Kaziranga
RT National park, Assam, India.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKK03535.1}.
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DR EMBL; JTGL01000159; KKK03535.1; -; Genomic_DNA.
DR RefSeq; WP_046569515.1; NZ_KQ058870.1.
DR AlphaFoldDB; A0A0M2RU01; -.
DR STRING; 1538294.LQ51_19580; -.
DR PATRIC; fig|1538294.3.peg.5142; -.
DR HOGENOM; CLU_005122_7_1_11; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000034330; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KKK03535.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 290..463
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 486..677
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 505..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 80472 MW; 49FBDA0525B33FF3 CRC64;
MTSEPSTVDT PLKKLVGERT AKALASHLDL HTAGDLIYHF PRRYDERGEH TDIRSLDVGE
QVTVLAQVQR TAVRPMRQRR GNLLEVTVGD GSGGVLTLTF FGNQAWRERE LRPGRWGLFA
GKVTEFRGKR QLNGPEYVLL GEGGDGEAAA NEEVEEFAGA LIPVYPAAAA VPTWVIARCV
RVVLDTFTPP ADPLPATVRA TRNLADIGAA LREIHRPSSK EALYRARRRL KWDEAFAVQL
TLVQRKHRAA AWPAKARPAR PGGLLDAFDA RLPYELTSGQ QVVGREIAAD LATAHPMHRL
LQGEVGSGKT LVALRAMLQV VDAGGQAALL APTEVLAAQH HRGIVELLGP LAQAGELGAA
DDATRVELVT GSLGAAARRR ALAEVAEGRA GIVLGTHALL YEGVDFHDLG LVVVDEQHRF
GVEQRDALRA KADQPPHVLV MTATPIPRTV AMTVYGDLEI STLSQLPQGR SPIASHVVPA
AEKPAFLDRA WRRLREEVGK GHQGYVVCPR IGDPGSGAGA ASAEAPDSGP GPVSDEEPPR
EDDNGRRPPL AVTEVAPLLA EGPLHGLRIG VLHGRLPADE KDAVMRAFAA GDLDVLVATT
VVEVGVNVPN ATMMVVLDAD RFGVSQLHQL RGRVGRGSAA GLCLLVTEAM EGSSARERLD
AVASTTDGFK LAELDLEQRR EGDVLGATQS GRRSHLRLLS LLRDTELIRD ARAEAIALVE
EDPELERHPA LAASVAALVD EERAEYLEKG
//
