ID A0A0M2S2J7_9ACTN Unreviewed; 427 AA.
AC A0A0M2S2J7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:KKK05403.1};
GN ORFNames=LQ51_13790 {ECO:0000313|EMBL:KKK05403.1};
OS Micromonospora sp. HK10.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1538294 {ECO:0000313|EMBL:KKK05403.1, ECO:0000313|Proteomes:UP000034330};
RN [1] {ECO:0000313|EMBL:KKK05403.1, ECO:0000313|Proteomes:UP000034330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK10 {ECO:0000313|EMBL:KKK05403.1,
RC ECO:0000313|Proteomes:UP000034330};
RA Talukdar M., Das D., Borah C., Deka Boruah H.P., Bora T.C., Singh A.K.;
RT "Draft genome sequence of Micromonospora HK10, isolated from Kaziranga
RT National park, Assam, India.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKK05403.1}.
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DR EMBL; JTGL01000125; KKK05403.1; -; Genomic_DNA.
DR RefSeq; WP_046566923.1; NZ_KQ058830.1.
DR AlphaFoldDB; A0A0M2S2J7; -.
DR STRING; 1538294.LQ51_13790; -.
DR PATRIC; fig|1538294.3.peg.3594; -.
DR HOGENOM; CLU_023810_3_2_11; -.
DR OrthoDB; 5193947at2; -.
DR Proteomes; UP000034330; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 322..414
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 427 AA; 45242 MW; 37D91694952CC138 CRC64;
MNICVVALGK IGLPLAVQFA SKGHRVIGAD VSERVVTLVN DGAVPFPGET DLDTKLKEAV
SAGLLTATTD TAAAVAEAEA VVVVVPLFVD ADGVPDFGWM DDATRAIARG LRPGTLVSYE
TTLPVGTTRN RWAPMLEEGS GLTAGTDFHL VFSPERVLTG RVFADLRRYP KLVGGIDEAS
AEHGVRFYEA VLDFDERGDL NRANGVWDLG SAEASELAKL AETTYRDVNI GLANQFARFA
DTVGVDVTKV IEACNTQPYS HIHQPGIAVG GHCIPIYPRM YLWNDPAATV VRSAREANAA
MPDYAVDLLA AAYGDLTGVG VLVLGAAYRG GVKETAFSGV FPTVEALRQR GAVPYVSDPM
YTNEELAAHG LPGYDGEPVG AAVIQADHAE YRTLAPADLP GVTVLVDGRR VTDPARWTGV
RRVVIGG
//
