ID A0A0M2U3R3_9FIRM Unreviewed; 306 AA.
AC A0A0M2U3R3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:KKM09301.1};
GN ORFNames=SY88_19925 {ECO:0000313|EMBL:KKM09301.1};
OS Clostridiales bacterium PH28_bin88.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1605376 {ECO:0000313|EMBL:KKM09301.1, ECO:0000313|Proteomes:UP000034222};
RN [1] {ECO:0000313|EMBL:KKM09301.1, ECO:0000313|Proteomes:UP000034222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Robbins S., Tyson G.;
RT "High quality genome sequence of Candidatus Suratobacter aromatica.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKM09301.1}.
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DR EMBL; LAKY01000067; KKM09301.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2U3R3; -.
DR STRING; 1605376.SY88_19925; -.
DR PATRIC; fig|1605376.3.peg.241; -.
DR Proteomes; UP000034222; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KKM09301.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000034222}.
FT DOMAIN 7..274
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 306 AA; 33234 MW; C5972924B9E903A9 CRC64;
MKMPASIVIC EVGPRDGLQN EKAMLTLEQK VELIERSALA GAKIIEIGSF VHPQAVPQMA
DTDEVARRIK RVEDVEYRAL VMNLRGLERA EAAGIKKVKL TVSASRAHSL SNLKRTPEEA
VRGFAECAEY AVTHGITLSG AISTSFGCPF EGRVPLEQVI SVISSFKEIG VNELSLSDTT
GMANPDQVYE YCLRVKEQFP NITWNLHFHN TRGMGLANVL AGMMAGIDRY DTCFAGLGGC
PFAPGATGNI ATEDLIHMCH EMGIETGYDL DQVISIGRYV QQIIGHDTAS FILKAGKNSD
IVCAQT
//
