ID A0A0M2VB69_9GAMM Unreviewed; 399 AA.
AC A0A0M2VB69;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=VT06_15735 {ECO:0000313|EMBL:KKO47704.1};
OS Arsukibacterium sp. MJ3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Arsukibacterium.
OX NCBI_TaxID=1632859 {ECO:0000313|EMBL:KKO47704.1, ECO:0000313|Proteomes:UP000034895};
RN [1] {ECO:0000313|EMBL:KKO47704.1, ECO:0000313|Proteomes:UP000034895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MJ3 {ECO:0000313|EMBL:KKO47704.1,
RC ECO:0000313|Proteomes:UP000034895};
RA Lylloff J.E., Skov L.B., Jepsen M., Hallin P.F., Sorensen S.J.,
RA Stougaard P., Glaring M.A.;
RT "Draft genome sequences of two protease-producing strains of
RT Arsukibacterium isolated from two cold and alkaline environments.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO47704.1}.
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DR EMBL; LAHP01000029; KKO47704.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2VB69; -.
DR STRING; 1632859.VT06_15735; -.
DR PATRIC; fig|1632859.4.peg.3259; -.
DR Proteomes; UP000034895; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000034895}.
FT DOMAIN 53..340
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 399 AA; 45987 MW; 0690CD4203078C7C CRC64;
MKPADCYDLK PLLIDTQLNY PILHQVLQNQ AAYKVQIIYT QIDRNADKII HFTDYQYGLN
ESEYFYPAST VKLPVSLLAL QWLEEQQVPA LTKDSIMLSG TNRSLQSSAL SDVTAENNLP
SIAHYIKKIL LVSDNDAYNR LYELLGQDYI NHQLQVKGLM NTVINHRLSL PLPEFEQRHF
NPIRFLDNDN NELLSLPARY TERQYLNTSK PMLGKAHIVN GKLVNIPMDF TDKNRFSLLD
FNSVLKRIIF PKAFKPLQQF NINQSSREFV LHHMTISPSD SLYPSYTVED YPDNYAKFLL
VAGDPATIPP HFNIVNKTGW AYGHAIDGAY IVDTDKNIEF LLVAVIYANQ NDILNDDKYQ
LEEIAKPFMR QLGQLIYSHE LKRRRAAVPA LTYQKTNRS
//
