ID A0A0M2XT30_9SPHI Unreviewed; 1393 AA.
AC A0A0M2XT30;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AAW12_21595 {ECO:0000313|EMBL:KKO88794.1};
OS Sphingobacterium sp. Ag1.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Sphingobacterium.
OX NCBI_TaxID=1643451 {ECO:0000313|EMBL:KKO88794.1, ECO:0000313|Proteomes:UP000034524};
RN [1] {ECO:0000313|EMBL:KKO88794.1, ECO:0000313|Proteomes:UP000034524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ag1 {ECO:0000313|EMBL:KKO88794.1,
RC ECO:0000313|Proteomes:UP000034524};
RA Pei D., Yu W., Kukutla P., Xu J.;
RT "Draft Genome Sequences of Sphingobacterium sp. Ag1 from Mosquito Anopheles
RT gambiae.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO88794.1}.
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DR EMBL; LBGU01000044; KKO88794.1; -; Genomic_DNA.
DR PATRIC; fig|1643451.3.peg.278; -.
DR Proteomes; UP000034524; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 8.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 3.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1393
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005647161"
FT TRANSMEM 810..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 864..1090
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1136..1251
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1282..1382
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1184
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1393 AA; 157850 MW; 40A6EB69C7D2FFD4 CRC64;
MPLRVFVRCF CCALALISVL YAQEKNYRFL HLDVNEGLSQ GSVFAIAQDY LGFMWIGTRD
GLNKYDARKF TIYRSNPQDS LSLEHNFIQA ITEDNKRRLW IGTMTGLNLY NRASDNFIRI
PLPTVESSSG KMDVNVHQIF QDSKGKIWIA TNIGLYKIKE GRHLEAELVF NEITVERSQG
KEYYRNFRTV YEDRRKRLWF CTDDAIVLMQ AASKDGNSLK VLRTYFKEKS VDNKVNQRFQ
AVLEVSPGIF WVGTKYNGIR IINENTGEIS SLTEAGNHTG LASQDVRSLK KTVDGKIWIG
TFNGLYVYQN GKLLFIQADD GNPNSLSNNS IRPIFQDKRG SIWIGTYFGG VNIYDKDIPN
FQNFTHQAKR NSLSYNVVSA FVENGMGELV IGTEGGGLNY FNRRTNSFFS ERHDKNNLNG
LSHNNVKSIC LDKEGNLWVG TYDGGLNLRR KGQQGYEHFR FDPNVSNGLA NNNVYAILED
RNGDIWIGTF GGGLQVLRKN QKVGSFQTFD VAGKQLSSNM VRALLEDSKG NLWIGTSNGL
NLKLAGTDKF VSFLNDKKDS LSISGNDIVS IHEDRKGQIW IGTYMGGLNR YLPEKKAFKR
FNERNGLPIN NVFAMLSDLK NKLWLSTNTG ISCFDPLSGH VRTYTKTDGL PGNEYIQNAA
AMLRDGKLAF GSFSGFTLFN PDSLSVNNYI PPIQFTELKL FNKTVLPGID AVIPKDISMM
DELILDHNQN VFSLEFSVLN YVHPEKNQYA YYLKGFDQDW NYVSNPVATY TNLDPGTYEL
WVKGANNDGV WNEKATVLKI KVLPAPWKTW WAYSGYFLLF AAAGFLIIRF FHGRNKLKQD
LLIRQIDSEK QEELHEAKLN FFTNISHEFR TPLSLIIGPL NQLKGDRSLS AYVQEHLGYA
TRNADRLMNL VNQLLDFRKH EGGKMKLFCQ KVHLATYLEN IRQNFHFIAE KNNIQFFLDN
KVSPNYVAGF DPEQFEKVLV NLIYNAFKFT DKGGKIKIQV ELEGEGELEK LLVSVWDSGR
GISPKDIPFV FEQFYQANTK GLSATNGGIG LALCRSIVQL HGGKLTVESN MAQETTDYNT
VFRISLPQSA VVIEELPVLT DTPGMICADP ADAGMPYVDT TKTAIERPAA EEDKPIILVA
EDNVELRCFL CENLRKKYIV LEANDGIEAL ELVQTKQPDI IISDVTMPNC DGITLLQQIK
NDSSSNHIPV ILLTARTADP YITEAFEIGT DDYITKPFSM PHLIQKISNI LQTRKRLEEK
FVQHYLLGAQ GTDLPERTRF LDQVLKIVEE NLGCEDFGVL DLTKAIGVSR SVLYRKIKQQ
TGLNLVEFIN MVRLKKAAYI LVNDTGLSIS EVAYQVGFND PKYFSKSFKK FYKESPRTYV
EKFGVKESSN LEK
//
