ID A0A0M2ZGD1_9MYCO Unreviewed; 525 AA.
AC A0A0M2ZGD1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=DNA polymerase {ECO:0000313|EMBL:ORA62283.1};
GN ORFNames=BST23_20400 {ECO:0000313|EMBL:ORA62283.1};
OS Mycolicibacterium elephantis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=81858 {ECO:0000313|EMBL:ORA62283.1, ECO:0000313|Proteomes:UP000192772};
RN [1] {ECO:0000313|EMBL:ORA62283.1, ECO:0000313|Proteomes:UP000192772}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FI-09383 {ECO:0000313|EMBL:ORA62283.1,
RC ECO:0000313|Proteomes:UP000192772};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC forks, which arise in vivo from mismatched or misaligned primer ends.
CC These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC exonuclease (proofreading) activity. May be involved in translesional
CC synthesis, in conjunction with the beta clamp from PolIII.
CC {ECO:0000256|ARBA:ARBA00025589}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORA62283.1}.
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DR EMBL; MVHP01000028; ORA62283.1; -; Genomic_DNA.
DR RefSeq; WP_046752496.1; NZ_MVHP01000028.1.
DR AlphaFoldDB; A0A0M2ZGD1; -.
DR STRING; 81858.BST23_20400; -.
DR OrthoDB; 5244088at2; -.
DR Proteomes; UP000192772; Unassembled WGS sequence.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03468; PolY_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR Pfam; PF00817; IMS; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..525
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038443203"
FT DOMAIN 29..153
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 525 AA; 56735 MW; D83E23ED140C948D CRC64;
MQSRVLAIWC MDWPAVAAAA AAGLPPTAPI AVTLANRVIA CSASARSAGV RRGLRRRESQ
ARCPELYVVT ADPARDARHF EAVTAAVDDL VPRAEVLRPG LLVLPIRGAA RYFGSEEAAA
QRLIDAVAAA GAECQVGIAD QLPTAVFAAR AGRIVEPGED AAFLSPLSIR QLAAEPSLAD
PGRQELADLL WRMGIRSIGQ FAALSRSDVA SRFGADGVVA HRFACGEPAR DPSGAEPAAE
LDAVMNCDPP IDRVDAAAFA GRSLASSLHR SLESSGVGCT RLAIHAVTAN GEELERVWRC
AEPLTEDATA DRVRWQLDGW LNRRRADERP TAPITMIRLR PVEVVSAEAL QLPLWGGIGE
EDRLRARRAL VRVQGLLGPE AVQMPVLSGG RGPAERITFT PLGDEQVPRA DPRQPWPGQL
PEPSPTVLLD DPVELVDADG NPVRVTARGL FSTDPWQLVA PGKGGRNGRL AWWAGPWPVD
ERWWDPQRAK VGRTARAQVL LDTEPAQALL LCYRQRRWYL EGVYE
//
