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Database: UniProt
Entry: A0A0M3F669_ENTCL
LinkDB: A0A0M3F669_ENTCL
Original site: A0A0M3F669_ENTCL 
ID   A0A0M3F669_ENTCL        Unreviewed;       644 AA.
AC   A0A0M3F669;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   08-MAY-2019, entry version 20.
DE   RecName: Full=Exoribonuclease 2 {ECO:0000256|HAMAP-Rule:MF_01036};
DE            EC=3.1.13.1 {ECO:0000256|HAMAP-Rule:MF_01036};
DE   AltName: Full=Exoribonuclease II {ECO:0000256|HAMAP-Rule:MF_01036};
DE            Short=RNase II {ECO:0000256|HAMAP-Rule:MF_01036};
DE            Short=Ribonuclease II {ECO:0000256|HAMAP-Rule:MF_01036};
GN   Name=rnb {ECO:0000256|HAMAP-Rule:MF_01036};
GN   ORFNames=OA46_07200 {ECO:0000313|EMBL:KKY88398.1};
OS   Enterobacter cloacae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX   NCBI_TaxID=550 {ECO:0000313|EMBL:KKY88398.1, ECO:0000313|Proteomes:UP000034104};
RN   [1] {ECO:0000313|EMBL:KKY88398.1, ECO:0000313|Proteomes:UP000034104}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH1 {ECO:0000313|EMBL:KKY88398.1,
RC   ECO:0000313|Proteomes:UP000034104};
RA   Lau Y.-Y.;
RT   "Whole Genome Sequence of Enterobacter cloacae CH1.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in mRNA degradation. Hydrolyzes single-stranded
CC       polyribonucleotides processively in the 3' to 5' direction.
CC       {ECO:0000256|HAMAP-Rule:MF_01036, ECO:0000256|SAAS:SAAS00050085}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to
CC         yield nucleoside 5'-phosphates.; EC=3.1.13.1;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01036,
CC         ECO:0000256|SAAS:SAAS01124678};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01036,
CC       ECO:0000256|SAAS:SAAS00089931}.
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family. RNase II
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_01036,
CC       ECO:0000256|SAAS:SAAS00555034}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKY88398.1}.
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DR   EMBL; JSWZ01000005; KKY88398.1; -; Genomic_DNA.
DR   RefSeq; WP_046885224.1; NZ_JSWZ01000005.1.
DR   EnsemblBacteria; KKY88398; KKY88398; OA46_07200.
DR   PATRIC; fig|550.369.peg.3909; -.
DR   Proteomes; UP000034104; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008859; F:exoribonuclease II activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01036; RNase_II; 1.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR040476; CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR013223; RNase_B_OB_dom.
DR   InterPro; IPR011804; RNase_II.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   InterPro; IPR004476; RNase_II/RNase_R.
DR   InterPro; IPR003029; S1_domain.
DR   Pfam; PF17876; CSD2; 1.
DR   Pfam; PF08206; OB_RNB; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00357; CSP; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; SSF50249; 4.
DR   TIGRFAMs; TIGR00358; 3_prime_RNase; 1.
DR   TIGRFAMs; TIGR02062; RNase_B; 1.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000034104};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01036,
KW   ECO:0000256|SAAS:SAAS00462075};
KW   Exonuclease {ECO:0000256|HAMAP-Rule:MF_01036,
KW   ECO:0000256|SAAS:SAAS00089915};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01036,
KW   ECO:0000256|SAAS:SAAS00446781, ECO:0000313|EMBL:KKY88398.1};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_01036,
KW   ECO:0000256|SAAS:SAAS00462054};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01036,
KW   ECO:0000256|SAAS:SAAS00462035}.
FT   DOMAIN       23     79       CSP. {ECO:0000259|SMART:SM00357}.
FT   DOMAIN      189    517       RNB. {ECO:0000259|SMART:SM00955}.
SQ   SEQUENCE   644 AA;  72740 MW;  C5A01FF1BD8DC198 CRC64;
     MLQDNPLLAQ LKQQLHSQTP RTEGVVKATE KGFGFLEVDA QKSYFIPPPQ MKKVMHGDRI
     VAVIHTEKER ESAEPEELIE PFLTRFVGKV QRKDDRLSIT PDHPLLKDAI QCRAARGVEH
     DFKEGDWAVA EMRRHPLKGD RSFYAELTHF ITFGDDHFVP WWVTLARHNL EKEAPNGVAT
     EMLDEGLERQ DLTALNFVTI DSASTEDMDD ALYVEERADG KLALTVAIAD PTAWVAEGSK
     LDDAAKIRAF TNYLPGFNIP MLPRELSDDL CSLRAMEVRP VLACRMTIAT DGTIEDDITF
     FAATIESKAK LVYDNVSDWL ENSGSWQPEN DAIADQIRLL HRVCQRRSEW RQTHALVFKD
     RPDYRFILGD KGEVLDIVAE PRRIANRIVE ESMIAANICA ARVLRDKLGF GIYNVHTGFD
     PANTEALAAL LKTHDVHVDP QEVLTLEGFC KLRRELDAQP TGFLDSRIRR FQSFAEISTE
     PGPHFGLGLE AYATWTSPIR KYGDMVNHRL LKAIIKGETI ARPGDETTLQ MAERRRLNRM
     AERDVGDWLY ARFLNDKAGT ETRFPAEIID VSRGGMRVRL VDNGAVAFIP APFLHAVRDE
     LVCSQENGTV QIKGETVYKV TEVIDVTIAE VRMETRSIIA RPAV
//
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